Cold pressor stimulus temperature and resting masseter muscle haemodynamics in normal humans
Cold pressor stimulus temperature and resting masseter muscle haemodynamics in normal humans
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DOI：
10.1016/s0003-9969(98)00072-7
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发表时间：
1998-11-01
影响因子：
3
通讯作者：
Yamashita, A
中科院分区：
文献类型：
--
作者：
Maekawa, K;Kuboki, T;Yamashita, A
据报道，冷加压刺激增加了人体骨骼肌中的交感神经活动。本研究采用近红外光谱分析技术，研究了刺激脊髓压力器对正常人右侧咬肌静息血流动力学的影响。9名健康、不吸烟、没有慢性肌肉疼痛或血管头痛病史的男性参加了研究。他们的右手在水浴(4，10，15摄氏度)中浸泡了整整1分钟。每次试验持续7min(刺激前1min，刺激中1min，刺激后5min)，三种试验温度和模拟试验采用严格随机的顺序。在每一次试验中，持续记录咬肌血红蛋白浓度和血氧饱和度，以及心率和血压。在完成四次测试后，每个参与者都产生并保持了30-S最大自愿咬合力。四项试验的数据经过基线校正，然后归一化为个体在30-S最大握力过程中的最高绝对血红蛋白和氧气信号。在冷压刺激期间，随着水温的降低，血红蛋白和血氧饱和度逐渐升高(Hb，p<；0.0001；O-2，p=0.0327)；在模拟试验中，几乎没有看到影响。心率和血压在刺激过程中也随着温度的降低而递增(心率，p=0.0013；收缩压，p=0.0042；舒张压，p=0.0156)。这些数据表明，冷加压刺激引起肌肉内血容量的显著增加，这似乎是由于局部血管扩张反应和心输出量增加所致。(C)1998爱思唯尔科学有限公司。保留所有权利。
Cold presser stimulation reportedly increases sympathetic nerve activity in human skeletal muscles. This study examined the effect of cord presser stimulation on the resting haemodynamics of the right masseter muscle in normal individuals, using near-infrared spectroscopy. Nine healthy non-smoking males with no history of chronic muscle pain or vascular headaches participated. Their right hand was immersed in a water bath (4, 10, 15 degrees C) for exactly 1 min. Each trial lasted 7 min (1 min before, I min during, 5 min after stimulation) and a strictly random order was utilized for the three test temperatures and the mock trial. Masseter muscle haemoglobin concentration and oxygen saturation, as well as heart rate and blood pressure, were continuously recorded in each trial. After completing the four trials, each participant produced and sustained a 30-s maximum voluntary clench in the intercuspal position. Data across the four trials were baseline-corrected and then magnitude-normalized to the individual's highest absolute haemoglobin and oxygen signal during the 30-s maximal clenching effort. Haemoglobin and oxygen saturation increased progressively during cold presser stimulation as the water temperature decreased (Hb, p < 0.0001; O-2, p = 0.0327); very little effect was seen during the mock trial. Heart rate and blood pressure also increased progressively during the stimulation as the temperature decreased (heart rate, p = 0.0013; systolic blood pressure, p = 0.0042; diastolic blood pressure, p = 0.0156). These data suggest that cold presser stimulation induces a strong increase in intramuscular blood volume which appears to be due to both a local vasodilative response and increased cardiac output. (C) 1998 Elsevier Science Ltd. All rights reserved.