Renal medullary hypoxia during experimental cardiopulmonary bypass: a pilot study

Renal medullary hypoxia during experimental cardiopulmonary bypass: a pilot study
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DOI:
10.1191/0267659105pf780oa
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发表时间:
2005-01-01
期刊:
影响因子:
1.2
通讯作者:
Grocott, HP
Grocott, HP
中科院分区:
医学4区
文献类型:
--
作者:
Stafford-Smith, M;Grocott, HP

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目的:探讨体外循环(CPB)对肾髓质氧合的影响。设计:观察性。设置:实验室。参与者:猪(n =3)。干预:全身麻醉诱导后,将Paratrend(TM)血气探针直接置入左肾髓质。两只动物接受90分钟的CPB,而第三只动物作为非CPB对照。还将探针放置在一只(CPB)动物的左肾盂中,以允许直接测量尿液PO。测量和主要结果:延髓缺氧(PO2
Objectives: To determine the effect of cardiopulmonary bypass (CPB) on renal medullary oxygenation. Design: Observational. Setting: Laboratory. Participants: Pigs (n =3). Interventions: Following induction of general anesthesia, a Paratrend(TM) blood gas probe was placed directly into the left renal medulla. Two animals were subjected to 90 min of CPB, while a third served as a non-CPB control. A probe was also placed in the left renal pelvis of one (CPB) animal to allow direct urine PO, measurements. Measurements and main results: Medullary hypoxia (PO2