Synthesis of 2,6-dimethyl-9-aryl-9-phosphabicyclo[3.3.1]nonanes: their application to asymmetric synthesis of chiral tetrahydroquinolines and relatives
Synthesis of 2,6-dimethyl-9-aryl-9-phosphabicyclo[3.3.1]nonanes: their application to asymmetric synthesis of chiral tetrahydroquinolines and relatives
复制标题
DOI：
10.1016/j.tet.2007.03.078
复制
发表时间：
2007-07-02
期刊：
影响因子：
2.1
通讯作者：
Hamada, Yasumasa
中科院分区：
文献类型：
--
作者：
Hara, Osamu;Koshizawa, Tomoaki;Hamada, Yasumasa
以1，5-环辛二烯为起始原料合成了2，6-二甲基-9-芳基-9-磷杂双环[3.3.1]壬烷，并将其应用于钯催化的烯丙基烷基化不对称环化反应，得到手性四氢喹啉及相关化合物。(c)2007爱思唯尔有限公司版权所有。
Synthesis of 2,6-dimethyl-9-aryl-9-phosphabicyclo[3.3.1]nonanes from 1,5-cyclooctadiene and their application to asymmetric cyclization leading to chiral tetrahydroquinolines and relatives through palladium-catalyzed allylic alkylation are described. (c) 2007 Elsevier Ltd. All rights reserved.