Disease-mediated inbreeding depression in a large, open population of cooperative crows
Disease-mediated inbreeding depression in a large, open population of cooperative crows
复制标题
大量开放的合作乌鸦群体中疾病介导的近交衰退
DOI：
--
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
I. Lovette
中科院分区：
文献类型：
--
作者：
Andrea K. Townsend;A. Clark;K. McGowan;E. Buckles;Andrew D. Miller;I. Lovette
疾病介导的近亲繁殖衰退是近亲群体生活的潜在成本，但其在野生种群中的一般程度尚不清楚。我们研究了近亲繁殖，生存和疾病之间的关系，312个后代，由35个父母对，在一个大的，开放的人口合作繁殖的美国乌鸦（乌鸦brachyrhynchos）。对亲子关系、父母相关系数和系谱信息的遗传分析表明，23%的父母二人组是一阶或二阶亲属。杂合性-杂合性相关表明，基于微卫星的个体杂合性指数可以预测该群体中个体全基因组杂合性。排除鸟类死亡的创伤后，生存概率较低的相对近交系鸟类在2-50个月后绑定：风险率为最近交系鸟类是170%以上的近亲繁殖指数值的范围内最少的近亲繁殖的鸟类。与疾病症状死亡的鸟类有较高的近亲繁殖指数比其他命运的鸟类。我们的研究结果表明，避免近亲繁殖和没有近亲繁殖抑郁症在大型，开放的人口不应该假设在类群与亲属为基础的社会系统，和微卫星为基础的个人杂合性指数可以是一个适当的工具，用于检查近亲繁殖抑郁症发生在乱伦和近亲繁殖的人口。
Disease-mediated inbreeding depression is a potential cost of living in groups with kin, but its general magnitude in wild populations is unclear. We examined the relationships between inbreeding, survival and disease for 312 offspring, produced by 35 parental pairs, in a large, open population of cooperatively breeding American crows (Corvus brachyrhynchos). Genetic analyses of parentage, parental relatedness coefficients and pedigree information suggested that 23 per cent of parental dyads were first- or second-order kin. Heterozygosity–heterozygosity correlations suggested that a microsatellite-based index of individual heterozygosity predicted individual genome-wide heterozygosity in this population. After excluding birds that died traumatically, survival probability was lower for relatively inbred birds during the 2–50 months after banding: the hazard rate for the most inbred birds was 170 per cent higher than that for the least inbred birds across the range of inbreeding index values. Birds that died with disease symptoms had higher inbreeding indices than birds with other fates. Our results suggest that avoidance of close inbreeding and the absence of inbreeding depression in large, open populations should not be assumed in taxa with kin-based social systems, and that microsatellite-based indices of individual heterozygosity can be an appropriate tool for examining the inbreeding depression in populations where incest and close inbreeding occur.