The Perioperative Pain Self-Management (PePS) randomized controlled trial protocol: Preventing chronic post-surgical pain and prolonged opioid use.
The Perioperative Pain Self-Management (PePS) randomized controlled trial protocol: Preventing chronic post-surgical pain and prolonged opioid use.
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围手术期疼痛自我管理（PePS）随机对照试验方案：预防慢性术后疼痛和长期使用阿片类药物。
DOI：
10.1016/j.cct.2022.106810
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发表时间：
2022-07
影响因子：
2.2
通讯作者：
Mosher, Hilary J.
中科院分区：
文献类型：
--
作者：
Hadlandsmyth, Katherine;Burgess, Diana J.;Leparski, Ryan F.;Odom, Annie S.;Campbell, Emily J.;Obrecht, Ashlie A.;Adamowicz, Jenna L.;Cho, Hyunkeun;Steffensmeier, Kenda Stewart;Johnson, Nicole L.;Richards, Christopher C.;Vander Weg, Mark W.;Lund, Brian C.;Yoon, Patrick;Mosher, Hilary J.
关键词：
全关节置换术是常见的骨科手术，具有发生慢性术后疼痛的风险。除了手术前和手术后疼痛的严重程度外，心理困扰(如焦虑、疼痛灾害化)也是手术后慢性疼痛的危险因素。认知行为疗法(CBT)治疗慢性疼痛是一种有经验支持的治疗慢性疼痛、功能障碍和相关痛苦的方法。虽然CBT已经被广泛应用于慢性疼痛患者，但将其作为一种预防性干预措施，针对手术后急性疼痛向慢性疼痛的过渡，是一种新的应用。围术期疼痛自我管理(PEPS)计划是一种基于CBT原则的疼痛自我管理干预。这一创新的干预措施简单、灵活，并可远程交付。目前的研究旨在确定与标准护理相比，PEPS在减少术后6个月显著手术部位疼痛方面的有效性。目前的研究还旨在评估后续实施的背景。本研究是一项混合型I型药效--准备实施试验。这是一项两点、单盲、双臂、平行、随机对照试验。手术患者将随机接受：1)PEPS加标准护理，或2)标准护理。主要终点是术后6个月手术部位疼痛的严重程度。这项研究的结果预计将导致支持一项简短的可扩展干预(PEPS)，该干预可以预防慢性疼痛的发展和手术后阿片类药物的长期使用，以及为后续实施提供信息的关键细节。
Total joint arthroplasties are common orthopedic surgeries that carry risk for developing chronic post-surgical pain. In addition to pre- and post-operative pain severity, psychological distress (e.g., anxiety, pain catastrophizing) is a risk factor for chronic postsurgical pain. Cognitive behavioral therapy (CBT) for chronic pain is an empirically supported approach to managing chronic pain, functional impairment, and related distress. While CBT has been used extensively in patients with established chronic pain, using it as a preventive intervention targeting the transition from acute to chronic postsurgical pain is a novel application. The Perioperative Pain Self-Management (PePS) program is a pain self-management intervention based on the principles of CBT. This innovative intervention is brief, flexible, and is delivered remotely. The current study aims to determine the efficacy of PePS compared to standard care on reducing the incidence of significant surgical site pain at 6-months post-surgery. The current study also aims to evaluate the context for subsequent implementation. This study is a hybrid type I efficacy-preparing for implementation trial. It is a two-site, single-blind, two-arm, parallel, randomized control trial. Surgical patients will be randomized to either receive: 1) PePS plus standard care, or 2) Standard care. The primary end point will be surgical site pain severity at 6-months post-surgery. Results from this study are expected to result in support for a brief scalable intervention (PePS) that can prevent the development of chronic pain and prolonged post-surgical opioid use, as well as key details to inform subsequent implementation.
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影响因子：
4.7
作者：
Knittle, Keegan;Maes, Stan;De Gucht, Veronique
通讯作者：
De Gucht, Veronique
DOI：
10.1136/bmj.g1251
发表时间：
2014-02-11
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Clarke H;Soneji N;Ko DT;Yun L;Wijeysundera DN
通讯作者：
Wijeysundera DN
DOI：
10.1002/art.10416
发表时间：
2002-06-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Astin, JA;Beckner, W;Berman, B
通讯作者：
Berman, B
DOI：
10.1016/0003-9993(94)90082-5
发表时间：
1994-10-01
影响因子：
4.3
作者：
CHIBNALL, JT;TAIT, RC
通讯作者：
TAIT, RC
影响因子：
3.6
作者：
Nicholas, Michael K.
通讯作者：
Nicholas, Michael K.