Cone beam computed tomography and histological evaluations of a straight electrode array positioning in temporal bones
Cone beam computed tomography and histological evaluations of a straight electrode array positioning in temporal bones
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DOI：
10.1080/00016489.2016.1227477
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发表时间：
2017-03-01
影响因子：
1.4
通讯作者：
Bernardeschi, Daniele
中科院分区：
文献类型：
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作者：
Mosnier, Isabelle;Celerier, Charlotte;Bernardeschi, Daniele
结论：CBCT 可以精确评估耳蜗导管的尺寸和形状，这对于电极阵列的长度选择和设计至关重要。这项放射组织学研究证实，CBCT 是临床研究中评估直电极阵列在耳蜗阶内位置的可靠工具。目的：通过将放射学图像与耳蜗植入颞骨的组织学分析进行比较，验证锥形束计算机断层扫描 (CBCT) 在评估耳蜗解剖结构和直电极阵列定位方面的可靠性。方法：对 4 名受试者在耳蜗植入前后的 8 块颞骨进行分析植入直电极阵列。植入前通过 CBCT 评估耳蜗的大小、180 度和 360 度耳蜗导管的尺寸和形状。然后对颞骨进行组织学分析以确定电极阵列的位置。植入后进行的 CBCT 评估电极阵列的标量定位，并与组织学研究进行比较。结果：CBCT 是一种可靠的放射学技术，不仅可以区分耳蜗尺寸的变异性，还可以区分耳蜗的大小和形状的变异性。组织学分析证实了 CBCT 在 7/8 颞骨中评估的电极阵列的标量位置，但 CBCT 未识别出软组织损伤，例如螺旋韧带的解剖。
Conclusion: CBCT allows a precise evaluation of the dimensions and of the shape of the cochlear duct that is of primary importance for the choice of the length and the design of the electrode array. This radio-histological study confirms that CBCT is a reliable tool to be used in clinical studies to evaluate the position of straight electrode arrays within the cochlear scala.Objective: To validate the reliability of cone beam computed tomography (CBCT) in the evaluation of cochlear anatomy and positioning of a straight electrode array, by comparing radiological images to histological analysis of cochlear implanted temporal bones.Methods: Eight temporal bones for four subjects were analysed before and after cochlear implantation with a straight electrode array. The size of the cochlea, the dimensions, and shape of the cochlear duct at 180 degrees and 360 degrees were evaluated on CBCT performed before implantation. Temporal bones then underwent histological analysis to determine the position of the electrode array. Scalar localization of the electrode array was assessed on CBCT performed after implantation, and compared with histological study.Results: CBCT is a reliable radiological technique to differentiate variability not only of cochlear dimensions, but also of size and shape of the cochlea. Histological analysis confirmed the scalar position of the electrode array assessed by the CBCT in 7/8 temporal bones, but soft tissue trauma such as dissection of the spiral ligament was not identified by the CBCT.