Dissociation between unconscious motor response facilitation and conflict in medial frontal areas
Dissociation between unconscious motor response facilitation and conflict in medial frontal areas
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DOI：
10.1111/j.1460-9568.2011.07941.x
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发表时间：
2012-01-01
影响因子：
3.4
通讯作者：
Garraux, Gaetan
中科院分区：
文献类型：
--
作者：
D'Ostilio, Kevin;Garraux, Gaetan
掩蔽的主要任务表明，没有被有意识地感知的感觉信息仍然可以调节行为。视觉运动启动行为表现的神经元相关性仍然存在争议，特别是关于额叶内侧区域活动变化的分布和方向(即增加或减少)。在这里，我们预测，这些不同的结果可以解释为这项任务中嵌入的两个自动和无意识的过程：反应冲突和促进。我们使用了事件相关功能磁共振成像(FMRI)，因为24名健康参与者必须尽可能快地对阈值下掩蔽主箭头后立即出现的目标箭头做出反应。原始目标关系定义了三种实验条件：相容、不相容和中性。在不相容的试验中，经典的视觉运动启动效应被重现，反应时间(RTS)相对较长。在不相容的试验中，比中性试验中更长的RTS与冲突相关网络中更强的血氧水平依赖(BOLD)活动具体相关，该网络包括前扣带回皮质和右侧额叶关联区。由于fMRI BOLD信号的重复抑制，相容试验中比中性试验中更短的RTS表明，促进运动反应与运动准备网络中包括内侧和外侧运动前皮质的激活减少有关。目前的结果为自动和无意识的视觉运动启动过程提供了新的见解，表明认知网络或运动网络参与其中，这取决于原始目标关系。
Masked prime tasks have shown that sensory information that has not been consciously perceived can nevertheless modulate behavior. The neuronal correlates of behavioral manifestations of visuomotor priming remain debated, particularly with respect to the distribution and direction (i.e. increase or decrease) of activity changes in medial frontal areas. Here, we predicted that these discrepant results could be accounted for by two automatic and unconscious processes embedded in this task: response conflict and facilitation. We used event-related functional magnetic resonance imaging (fMRI), as 24 healthy participants had to respond, as fast as possible, to a target arrow presented immediately after a subliminal masked prime arrow. There were three experimental conditions defined by the primetarget relationship: compatible, incompatible, and neutral. The classical visuomotor priming effect was reproduced, with relatively longer reaction times (RTs) in incompatible trials. Longer RTs in incompatible than in neutral trials were specifically associated with stronger blood oxygen level-dependent (BOLD) activity in a conflict-related network comprising the anterior cingulate cortex and right frontal associative areas. Motor response facilitation as shown by shorter RTs in compatible than in neutral trials was associated with reduced activation in a motor preparation network including the medial and lateral premotor cortices, as a result of the repetition suppression of the fMRI BOLD signal. The present results provide new insights into automatic and unconscious visuomotor priming processes, suggesting an involvement of either a cognitive or motor network, depending on the primetarget relationship.