Prevalence of metabolic syndrome and its associated factors in overweight and obese adolescents
Prevalence of metabolic syndrome and its associated factors in overweight and obese adolescents
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DOI：
10.1515/jpem-2019-0369
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发表时间：
2020-02-01
影响因子：
1.4
通讯作者：
Nucci, Luciana B.
中科院分区：
文献类型：
--
作者：
Dejavitte, Rosemeire A. S.;Enes, Carla C.;Nucci, Luciana B.
背景：代谢综合征（MetS）不仅是成年期的问题，而且已经存在于儿童和青少年中。本研究的目的是估计代谢综合征在青少年的患病率，并确定相关factors.Methods：这是一个横断面研究与354超重和肥胖的学龄青少年（10 - 19岁）。收集了社会人口学、人体测量学、临床、生化和生活方式变量。根据国际糖尿病联合会（IDF）提出的标准确定MetS。采用多因素Logistic回归模型分析代谢综合征的危险因素。结果：代谢综合征的患病率为9.6%。在MetS青少年中，所有人都有低高密度脂蛋白胆固醇（HDL-c），而76.5%有高血糖，38.2%有高甘油三酯血症。只有12.1%的人没有任何MetS组分，而40%的人至少有两种组分。多因素分析显示，女孩是一个保护因素（比值比[OR]= 0.29，置信区间[CI]= 0.13 - 0.65），而肥胖（OR = 3.63，CI = 1.62-8.17）和活动不足OR = 4.60，CI = 1.01-20.96。结论：肥胖和活动不足的男性青少年更易患代谢综合征。早期识别代谢综合征的成分，特别是在肥胖青少年中，是预防成年期心血管并发症的重要工具。
Background: Metabolic syndrome (MetS) is not only a problem of adulthood but is already present in children and adolescents. The aim of this study was to estimate the prevalence of MetS in adolescents and to identify the associated factors.Methods: This was a cross-sectional study with 354 overweight and obese school-aged adolescents (10-19 years). Sociodemographic, anthropometric, clinical, biochemical and lifestyle variables were collected. MetS was identified according to the criteria proposed by the International Diabetes Federation (IDF). Multivariate logistic regression models were used to examine the associations between risk variables and MetS.Results: The prevalence of MetS was 9.6%. Among adolescents with MetS, all of them had low high-density lipoprotein cholesterol (HDL-c), while 76.5% had hyperglycemia and 38.2% had hypertriglyceridemia. Only 12.1% did not present any component of MetS, while 40% had at least two components. Multivariate analysis showed that being a girl was a protective factor (odds ratio [OR] =0.29, confidence interval [CI] = 0.13-0.65) for the presence of MetS, while obesity (OR= 3.63, CI=1.62-8.17) and being insufficiently active (OR=4.60, CI=1.01-20.96) were the risk factors for MetS.Conclusions: Obese and insufficiently active male adolescents are more likely to have MetS. Early identification of MetS components, especially among obese adolescents, is an important tool for the prevention of cardiovascular complications in adult life.