Comparison of coronary CT angiography-based and invasive coronary angiography-based quantitative flow ratio for functional assessment of coronary stenosis: A multicenter retrospective analysis

Comparison of coronary CT angiography-based and invasive coronary angiography-based quantitative flow ratio for functional assessment of coronary stenosis: A multicenter retrospective analysis
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基于冠状动脉CT血管造影和基于侵入性冠状动脉血管造影的定量血流比对冠状动脉狭窄功能评估的比较:多中心回顾性分析

DOI:
10.1016/j.jcct.2022.06.002
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发表时间:
2022-12-12
影响因子:
5.4
通讯作者:
Tu, Shengxian
Tu, Shengxian
中科院分区:
医学3区
文献类型:
--
作者:
Li, Zehang;Li, Guanyu;Tu, Shengxian

文献摘要

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背景:本研究旨在评价基于冠状动脉CT血管造影(CTA)的定量血流比(quantitative flow ratio, QFR),即CT-QFR的诊断性能,并以血流储备分数(fractional flow reserve, FFR)为参考标准,与基于有创冠状动脉造影(ICA)的Murray law QFR (mu QFR)进行比较。方法:回顾性分析2个月内接受冠状动脉CTA、ICA和压力线FFR评估的患者。CT-QFR和mu QFR采用盲法计算,并与FFR进行比较,均采用相同的截止值
Background: The aim of this study was to evaluate the diagnostic performance of coronary CT angiography (CTA)-based quantitative flow ratio (QFR), namely CT-QFR, and compare it with invasive coronary angiography (ICA)-based Murray law QFR (mu QFR), using fractional flow reserve (FFR) as the reference standard.Methods: Patients who underwent coronary CTA, ICA and pressure wire-based FFR assessment within two months were retrospectively analyzed. CT-QFR and mu QFR were computed in blinded fashion and compared with FFR, all applying the same cut-off value of