REACTION OF THE MYOCARDIUM TO CRYOSURGERY - ELECTROPHYSIOLOGY AND ARRHYTHMOGENIC POTENTIAL
REACTION OF THE MYOCARDIUM TO CRYOSURGERY - ELECTROPHYSIOLOGY AND ARRHYTHMOGENIC POTENTIAL
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DOI：
10.1161/01.cir.59.2.364
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发表时间：
1979-01-01
期刊：
影响因子：
37.8
通讯作者：
GALLAGHER, JJ
中科院分区：
文献类型：
--
作者：
KLEIN, GJ;HARRISON, L;GALLAGHER, JJ
在6只犬上研究了左心室冷冻损伤的急性和慢性电生理效应。冷冻后1 ~ 4天内，所有犬均出现频发室性早搏（VPB），5只犬出现室性心动过速，1只犬冷冻前即有VPB，冷冻后1周仍有VPB。2只对照犬无室性早搏。另外两只犬在冷冻损伤后立即进行了心外膜和透壁标测研究;这些动物的VPB起源于冷冻损伤的边缘。在正常窦性心律下，慢性冷冻损伤不会改变心外膜激动顺序。慢性冷冻损伤的边界区与正常电位外记录的病变和外在电位内记录划定。
The acute and chronic electrophysiological effects of a cryolesion produced in the left ventricle were studied in 6 dogs. All dogs had frequent ventricular premature beats (VPB) and 5 had ventricular tachycardia during the 1st 4 days after the cryolesion, 1 dog continued to have VPB after 1 wk this dog had VPB before cryosurgery. Two control dogs did not have VPB. Two additional dogs underwent epicardial and transmural mapping studies immediately after production of a cryolesion; VPB in these animals originated at the border of the cryolesion. Epicardial activation sequence during normal sinus rhythm was not altered by chronic cryolesion. The border zone of the chronic cryolesion was demarcated with normal potentials recorded outside of the lesion and extrinsic potentials recorded within.