Alkaline stress response in Enterococcus faecalis: Adaptation, cross-protection, and changes in protein synthesis

Alkaline stress response in Enterococcus faecalis: Adaptation, cross-protection, and changes in protein synthesis
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DOI:
10.1128/aem.63.2.812-814.1997
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发表时间:
1997-02-01
影响因子:
4.4
通讯作者:
Auffray, Y
Auffray, Y
中科院分区:
生物学2区
文献类型:
--
作者:
Flahaut, S;Hartke, A;Auffray, Y

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本文研究了粪肠球菌的碱休克反应。细胞适应的最佳pH值为10.5耐受pH值为11.9的条件,但获得酸损伤的敏感性。胁迫蛋白的分析表明,37个多肽扩增。其中两个是DnaK和GroEL。综合结果表明,胆汁盐和碱性应激反应密切相关。
The alkaline shock response in Enterococcus faecalis was studied in this work. Cells adapted to an optimum pH of 10.5 were tolerant to pH 11.9 conditions but acquired sensitivity to acid damage. An analysis of stress proteins revealed that 37 polypeptides were amplified. Two of these are DnaK and GroEL. The combined results show that bile salts and alkaline stress responses are closely related.