Dynamic proteins and a cytoskeleton in bacteria
Dynamic proteins and a cytoskeleton in bacteria
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DOI：
10.1038/ncb0303-175
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发表时间：
2003-03-01
影响因子：
21.3
通讯作者：
Errington, J
中科院分区：
文献类型：
--
作者：
Errington, J
现代荧光显微镜方法在细菌中的应用彻底改变了我们对细菌亚细胞组织的看法。现在已知许多蛋白质都能精确地靶向细胞中的特定位置，或者在定位中经历快速的定向变化。微管蛋白（FtsZ）和肌动蛋白（MreB）的结构和功能同源物现在无可争议地存在于细菌中，推翻了教科书中认为细胞骨架是真核生物所特有的观点。这些进展正在刺激人们对细菌中各种基本过程是如何组织的进行彻底的反思。
The application of modern fluorescence microscopic methods to bacteria has revolutionized our view of their subcellular organization. Many proteins are now known to be targeted with exquisite precision to specific locations in the cell, or to undergo rapid directed changes in localization. Structural and functional homologues of tubulin (FtsZ) and actin (MreB) are now indisputably present in bacteria, overturning the textbook view that the cytoskeleton is unique to eukaryotes. These advances are stimulating a radical rethink about how various fundamental processes are organised in bacteria.