Response-locked theta dissociations reveal potential feedback signal following successful retrieval.
Response-locked theta dissociations reveal potential feedback signal following successful retrieval.
复制标题
响应锁定 theta 解离揭示了成功检索后的潜在反馈信号。
DOI：
10.1101/2024.01.11.575166
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Long,NicoleM
中科院分区：
文献类型：
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作者：
Smith,DevynE;Wheelock,JustinR;Long,NicoleM
成功的记忆提取依赖于记忆过程来访问内部表征和决策过程来评估和响应所访问的表征，这两者都由theta（4-8 Hz）活动的波动支持。然而，记忆反应后决策过程的参与程度尚不清楚。在这里，我们记录了头皮脑电图（EEG），而人类参与者进行识别记忆任务。我们专注于响应锁定的数据，使我们能够研究在记忆响应之前和之后发生的过程。我们复制以前的工作，发现之前的记忆响应θ功率是更大的识别以前研究的项目（命中）相对于拒绝新的诱惑（正确的拒绝; CR）。在记忆反应之后，θ功率解离“翻转”，由此相对于命中，CR的θ功率更大。我们发现，响应后的“翻转”是更强大的命中，承诺迅速，潜在地反映了一个积极的反馈信号，强烈记得的经验。我们的研究结果表明，有潜在的不同的过程发生之前和之后的记忆反应，成功的记忆检索调制。
Successful memory retrieval relies on memory processes to access an internal representation and decision processes to evaluate and respond to the accessed representation, both of which are supported by fluctuations in theta (4–8 Hz) activity. However, the extent to which decision-making processes are engaged following a memory response is unclear. Here, we recorded scalp electroencephalography (EEG) while human participants performed a recognition memory task. We focused on response-locked data, allowing us to investigate the processes that occur prior to and following a memory response. We replicate previous work and find that prior to a memory response theta power is greater for identification of previously studied items (hits) relative to rejection of novel lures (correct rejections; CRs). Following the memory response, the theta power dissociation “flips” whereby theta power is greater for CRs relative to hits. We find that the post-response “flip” is more robust for hits that are committed quickly, potentially reflecting a positive feedback signal for strongly remembered experiences. Our findings suggest that there are potentially distinct processes occurring before and after a memory response that are modulated by successful memory retrieval.