The Clinical Overlap of Multiple Sclerosis and Headache
The Clinical Overlap of Multiple Sclerosis and Headache
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DOI：
10.1111/j.1526-4610.2012.02243.x
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发表时间：
2012-10-01
期刊：
影响因子：
5
通讯作者：
Applebee, Angela
中科院分区：
文献类型：
--
作者：
Applebee, Angela
多发性硬化症（MS）和偏头痛并存于许多年轻女性患者。这是巧合还是因果关系尚不清楚。MS复发和偏头痛先兆的症状和体征可能相似，应通过仔细的病史和检查来区分，以确保正确的诊断和治疗。磁共振成像上的白质病变对每个实体都有特定的模式，也需要仔细解释。虽然偏头痛和多发性硬化症之间没有明确的联系，但已有大量研究报道评估了风险、患病率和因果关系。使这些评估复杂化的是用于治疗多发性硬化症的疾病修饰疗法，这些疗法已知与引起头痛有关。最近发展的新的治疗方案，多发性硬化症要求从业者意识到多药和潜在的药物相互作用。
Multiple sclerosis (MS) and migraine headache coexist in many young female patients. Whether this is coincidental or causally linked remains unclear. The presenting symptoms and signs of MS relapse and migraine aura can be similar and should be differentiated by careful history and examination to ensure proper diagnosis and treatment. White matter lesions on magnetic resonance imaging have specific patterns for each entity and also need to be interpreted carefully. Although a clear link has not been established between migraine and MS, numerous studies have been reported assessing risks, prevalence, and causation. Complicating these assessments are the disease-modifying therapies used to treat MS which have been known to be implicated in causing headache. The recent development of novel treatment options for MS requires practitioners to be aware of polypharmacy and potential drug interactions.