Psoriasiform lupus vulgaris with 30 years duration
Psoriasiform lupus vulgaris with 30 years duration
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银屑病样寻常狼疮病程 30 年
DOI：
10.1080/00365540500404045
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发表时间：
2006
影响因子：
--
通讯作者：
J. Szepietowski
中科院分区：
文献类型：
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作者：
A. Reich;Monika Kobierzycka;M. Cisło;R. Schwartz;J. Szepietowski
寻常型狼疮是一种进行性皮肤结核，发生在具有中等到高度免疫力的人身上。它是最常见的皮肤结核类型。寻常型狼疮可以被其他几种皮肤病所模仿，一位69岁的女性被描述为有非常长的广泛浸润性皮损和大量鳞屑的病史。病变位于右臂和前臂，以及右侧胸部表面。散光试验呈阳性。此外，右肘窝区可见一大块萎缩性疤痕，导致右肘关节痉挛。组织病理学检查强烈提示结核病的诊断。经聚合酶链式反应检测，确诊为肺结核。采用乙胺丁醇1250 mg/d、利福平600 mg/d、异烟肼300 mg/d的综合化疗方案成功地治疗皮损。
Lupus vulgaris is a progressive form of cutaneous tuberculosis occurring in a person with a moderate to high degree of immunity. It is the most common type of cutaneous tuberculosis. Lupus vulgaris can be mimicked by several other skin conditions, and a 69-y-old female is described with an extremely long history of extensive infiltrative skin lesions with abundant scaling. The lesions were localized on the right arm and forearm, and on the right lateral surface of the chest. The diascopic test was positive. Moreover, a large atrophic scar was seen in the region of right cubital fossa resulting in contracture of the right elbow joint. The histopathology strongly suggested the diagnosis of tuberculosis. The final diagnosis of tuberculosis was confirmed by PCR examination. A polychemotherapeutic regimen (ethambutol 1250 mg/d, rifampicin 600 mg/d and isoniazid 300 mg/d) was successfully employed for the treatment of skin lesions.