Conscious appreciation of the effects produced by independent changes of ventilation volume and of end‐tidal pCO2 in paralysed patients
Conscious appreciation of the effects produced by independent changes of ventilation volume and of end‐tidal pCO2 in paralysed patients
复制标题
有意识地评估瘫痪患者通气量和呼气末 pCO2 的独立变化所产生的影响
DOI：
--
复制
发表时间：
1959
期刊：
影响因子：
--
通讯作者：
J. Spalding
中科院分区：
文献类型：
--
作者：
L. Opie;A. Smith;J. Spalding
这些病人因小儿麻痹症而严重瘫痪。每个人都接受了Radcliffe呼吸泵（Russell，Schuster，Smith和Spalding，1956）通过在气管中提供气密密封的带翻边的气管切开管（Spalding和Smith，1956）进行的人工通气。在室温下用Parkinson &科万型CD气量计测量10次呼吸的呼气潮气量。呼吸频率为每分钟16次。通过机械采样器（Smith、Schuster和Spalding，1959）获得潮气末样本，并通过连续流动电桥分析仪（Cunningham、Cormack、O'Riordan、Jukes和Lloyd，1957）测定p0C2。通过向吸入空气中加入CO来提高潮气末pCO2，并通过改变吸气压力来改变潮气量。进行这些更改的控件对患者是隐藏的。在整个检查过程中，要求患者报告任何异常感觉。呼吸急促是我们特别感兴趣的感觉，但有关这方面的问题被特别避免。
The patients were severely paralysed by poliomyelitis. Each received artificial ventilation from a Radcliffe respiration pump (Russell, Schuster, Smith & Spalding, 1956) through a cuffed tracheotomy tube (Spalding & Smith, 1956) which provided an air-tight seal in the trachea. The expired tidal volume was measured over 10 breaths at room temperature with a Parkinson & Cowan type CD gas-meter. The respiratory frequency was 16 per minute. End-tidal samples were obtained by a mechanical sampler (Smith, Schuster & Spalding, 1959) and p0C2 was determined by a continuous flow-bridge analyser (Cunningham, Cormack, O'Riordan, Jukes & Lloyd, 1957). The end-tidal pCO2 was raised by adding CO. to the inspired air, and the tidal volume was altered by varying the inspiratory pressure. The controls for making these changes were hidden from the patient. Throughout the examination the patient was asked to report any unusual sensations. Shortness of breath was the sensation in which we were particularly interested, but questions about this were specifically avoided.