Bullous pemphigoid with the deposition of IgG2 but not IgG1, IgG3 nor IgG4 autoantibodies at the basement membrane zone
Bullous pemphigoid with the deposition of IgG2 but not IgG1, IgG3 nor IgG4 autoantibodies at the basement membrane zone
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大疱性类天疱疮，基底膜区有 IgG2 沉积，但没有 IgG1、IgG3 或 IgG4 自身抗体沉积
DOI：
10.1111/jdv.14920
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发表时间：
2018
影响因子：
9.2
通讯作者：
Shimizu H.
中科院分区：
文献类型：
--
作者：
Yoshimoto N.;Ujiie H.;Zheng M.;Iwata H.;Kosumi H.;Hata H.;Shimizu H.
这篇文章介绍了一个66岁的妇女的案例研究，她的左腿上有一个水疱和抑郁症的历史。报告中提到，来自水疱的皮肤活检标本显示与血管周围炎症相关的表皮下分离。患者后来被诊断为由IgG2自身抗体诱导的大疱性类天疱疮（BP）。它告知患者曾接受局部丙酸氯倍他索治疗。
The article presents a case study of a 66-year-old woman with a blister on her left leg and history of depression. It mentions that skin biopsy specimen from the blister showed subepidermal separation associated with perivascular inflammation. The patient was later diagnosed with bullous pemphigoid (BP) induced by IgG2 autoantibodies. It informs that the patient was treated with topical clobetasol propionate.