Evaluation of ocular blood flow over time in a treated retinal arterial macroaneurysm using laser speckle flowgraphy.
Evaluation of ocular blood flow over time in a treated retinal arterial macroaneurysm using laser speckle flowgraphy.
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DOI：
10.1016/j.ajoc.2021.101022
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发表时间：
2021-03
影响因子：
--
通讯作者：
Nagaoka T
中科院分区：
文献类型：
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作者：
Hanazaki H;Yokota H;Aso H;Yamagami S;Nagaoka T
目的：报道激光散斑血流图(LSFG)检测视网膜大动脉瘤(RAM)治疗后眼部血流量随时间的变化。患者为72岁女性，左眼视力突然下降。眼底检查显示RAM和玻璃体出血(VH)，并在一个月后恶化。玻璃体切割术去除VH，玻璃体腔内注入20%六氟化硫。两周后VH复发，在第二次玻璃体切割术中，RAM被发现从四分之一椎间盘直径(DD)扩大到3个DD。在接下来的两周内，RAM自发缩小到一个DD，没有复发的VH。从第二次玻璃体切割术后4周开始，我们对视网膜进行了连续的LSFG检查，发现随着视网膜的继续内化，视网膜的平均模糊率(MBR)和视网膜小动脉和引流小静脉的视网膜血流量(RFV)都有所下降。LSFG测量的MBR、小动脉和小静脉RFV均随内脏退缩而减少。LSFG对血流的纵向跟踪可能有助于无创性评估RAMS的稳定性。
To report the changes over time in ocular blood flow quantified by laser speckle flowgraphy (LSFG) in a treated large retinal arterial macroaneurysm (RAM). A 72-year old female presented with sudden decreased vision in the left eye. Fundus examination revealed a RAM and vitreous hemorrhage (VH), which worsened over one month. A vitrectomy was performed to remove the VH, with 20% sulfur hexafluoride injected into the vitreous cavity. The VH recurred two weeks later and the RAM was found to have enlarged from one-quarter disc diameter (DD) to three DDs during a second vitrectomy. The RAM subsequently shrunk spontaneously to one DD without recurrent VH during the following 2 weeks. Beginning 4 weeks after the second vitrectomy we performed serial LSFG examinations of the RAM and found that the mean blur rate (MBR) of the RAM and retinal flow volume (RFV) in both the feeding arteriole and draining venule decreased as the RAM continued to involute. MBR and arteriolar and venular RFV measured by LSFG decreased with RAM involution. Longitudinal followup of blood flow by LSFG may be useful for noninvasive evaluation of the stability of RAMs.