Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis

Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis
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DOI:
10.1136/gutjnl-2020-322179
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发表时间:
2021-03-01
期刊:
GUT
影响因子:
24.5
通讯作者:
Sharp, Linda
Sharp, Linda
中科院分区:
医学1区
文献类型:
--
作者:
Rutter, Matthew D.;Brookes, Matthew;Sharp, Linda

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目的COVID-19大流行对内镜服务产生了重大的全球影响。这种能力的降低,沿着公众在大流行期间不愿接受内窥镜检查,可能导致癌症诊断延迟导致死亡率过高。利用英国国家内镜数据库(NED),我们对疫情对内镜服务和内镜癌症诊断的影响进行了首次全国性分析。设计我们开发了一个NED COVID-19模块,其中包含所有内镜手术的手术级数据。三个期间被指定为:新冠肺炎前(2020年1月6日至3月15日)、过渡期(3月16日至22日)及新冠肺炎影响期(3月23日至5月31日)。进行了国家、区域和程序特定分析。结果2009年1月至2010年12月期间,北京市共开展内镜检查35 478例次,平均每周检出癌例数、漏诊癌例数和检出率。受COVID影响期间的活动减少至COVID前水平的12%;在其低点,活动仅为5%,到研究结束时恢复至COVID前活动的20%。尽管更具选择性的审查显著提高了每一程序的癌症检出率(COVID前1.91%; COVID影响6.61%; p
Objective The COVID-19 pandemic has had a major global impact on endoscopic services. This reduced capacity, along with public reluctance to undergo endoscopy during the pandemic, might result in excess mortality from delayed cancer diagnosis. Using the UK's National Endoscopy Database (NED), we performed the first national analysis of the impact of the pandemic on endoscopy services and endoscopic cancer diagnosis.Design We developed a NED COVID-19 module incorporating procedure-level data on all endoscopic procedures. Three periods were designated: pre-COVID (6 January 2020 to 15 March), transition (16-22 March) and COVID-impacted (23 March-31 May). National, regional and procedure-specific analyses were performed. The average weekly number of cancers, proportion of missing cancers and cancer detection rates were calculated.Results A weekly average of 35 478 endoscopy procedures were performed in the pre-COVID period. Activity in the COVID-impacted period reduced to 12% of pre-COVID levels; at its low point, activity was only 5%, recovering to 20% of pre-COVID activity by study end. Although more selective vetting significantly increased the per-procedure cancer detection rate (pre-COVID 1.91%; COVID-impacted 6.61%; p