Alcohol impairment of behavior in men and women
Alcohol impairment of behavior in men and women
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DOI：
10.1111/j.1360-0443.2004.00805.x
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发表时间：
2004-10-01
期刊：
影响因子：
6
通讯作者：
Weafer, J
中科院分区：
文献类型：
--
作者：
Fillmore, MT;Weafer, J
研究表明，酒精会损害人类抑制行为反应的能力，一些证据表明，男性可能比女性表现出更大的损害。本研究比较了男性和女性在血液酒精浓度相当的情况下，中等剂量的酒精损害其抑制控制的程度。（0.65 g/kg）和安慰剂，并进行提示去/不-去的任务，测量的能力，抑制和执行的行为responses.Findings的行为反应是prepotent（即煽动），男性表现出更大的损害抑制控制下酒精比女性。男性也报告了更大的主观刺激酒精与女性相比，谁报告更多的镇静从drug.Conclusions酒精损害的抑制控制的性别差异可以解释的观察，在酒精下的抑制和攻击性行为更明显的男性比女性。
Aims Studies have shown that alcohol impairs the ability to inhibit behavioral responses in humans and some evidence suggests that men might display greater impairment than women. The present study compared men and women in the degree to which a moderate dose of alcohol impaired their inhibitory control at comparable blood alcohol concentrations.Design Twelve male and 12 female adult social drinkers received a moderate dose of alcohol (0.65 g/kg) and a placebo in a counterbalanced order and performed a cued go/no-go task that measured the ability to inhibit and execute behavioral responses.Findings When the behavioral response was pre-potent (i.e. instigated), men displayed greater impairment of inhibitory control under alcohol than women. Men also reported greater levels of subjective stimulation from alcohol compared with women, who reported more sedation from the drug.Conclusions A gender difference in alcohol impairment of inhibitory control could account for observations that disinhibited and aggressive behaviors under alcohol are more pronounced in men than in women.