Early contrast-enhanced MRI predicts late functional recovery after reperfused myocardial infarction
Early contrast-enhanced MRI predicts late functional recovery after reperfused myocardial infarction
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DOI：
10.1161/01.cir.99.6.744
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发表时间：
1999-02-16
期刊：
影响因子：
37.8
通讯作者：
Reichek, N
中科院分区：
文献类型：
--
作者：
Rogers, WJ;Kramer, CM;Reichek, N
背景--我们观察到再灌注心肌梗死（MI）后早期MRI增强的3种异常模式：（1）正常首过信号增强缺失（HYPO），（2）正常首过信号后延迟图像高增强信号（HYPER），或（3）正常首过信号增强缺失和延迟高增强信号（COMB）。本研究探讨了这些模式之间的关联，在第一周后MI和心肌收缩功能的后期恢复，通过使用磁共振心肌组织taging.Methods和Results-Seventeen患者（14名男子）的平均年龄为53 +/- 12岁进行了研究后，再灌注第一MI。造影剂增强图像在钆团注后立即采集，7+/-2分钟后采集。在第1周和第7周采集标记图像。在第1周和第7周，在显示HYPER、COMB或HYPO对比模式的区域和远端区域（REMOTE）测量环周节段缩短（%S）。第1周，HYPER、COMB和HYPO的%S降低（分别为9+/-8%，7+/-6%和5+/-4%），低于REMOTE（18+/-6%）。P
Background-We have observed 3 abnormal patterns on contrast-enhanced MRI early after reperfused myocardial infarction (MI): (1) absence of normal first-pass signal enhancement (HYPO), (2) normal first pass signal followed by hyperenhanced signal on delayed images (HYPER), or (3) both absence of normal first-pass enhancement and delayed hyperenhancement (COMB). This study examines the association between these pattern in the first week after MI and late recovery of myocardial contractile function by use of magnetic resonance myocardial tissue tagging.Methods and Results-Seventeen patients (14 men) with a mean age of 53 +/- 12 years were studied after a reperfused first MI. Contrast-enhanced images were acquired immediately after bolus administration of gadolinium and 7+/-2 minutes later. Tagged images were acquired at weeks 1 and 7. Circumferential segment shortening (%S) was measured in regions displaying HYPER, COMB, or HYPO contrast patterns and in remote regions (REMOTE) at weeks 1 and 7. at week 1, %S was depressed in HYPER, COMB, and HYPO (9+/-8%, 7+/-6% and 5+/-4% respectively) and were less than REMOTE ( 18+/-6%. P