Diabetic ketoacidosis risk during the COVID-19 pandemic.
Diabetic ketoacidosis risk during the COVID-19 pandemic.
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DOI：
10.1016/s2213-8587(21)00241-2
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发表时间：
2021-10
期刊：
影响因子：
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通讯作者：
Umpierrez GE
中科院分区：
文献类型：
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作者：
Vellanki P;Umpierrez GE
糖尿病酮症酸中毒（DKA）是糖尿病患者最常见的急性高血糖急症。DKA最常发生在1型糖尿病患者中，但也可发生在压力条件下控制不良的2型糖尿病患者中。1研究报告称，1型或2型糖尿病合并COVID-19感染患者的DKA患病率增加。与未感染COVID-19的患者相比，患有严重高血糖症和DKA并感染COVID-19的住院患者的并发症严重程度增加，死亡率更高。2 Shivani Misra及其同事3的文章检查了英格兰全国范围数据库中以DKA编码的急诊入院率。该研究集中于2019冠状病毒病大流行期间的三个独立时间段：2020年3月1日至6月30日（第一波），2020年7月1日至10月31日（第一波后），2020年11月1日至2021年2月28日（第二波），并将这些时期DKA入院的发生率与治疗前3年同等时期的平均发生率进行比较。
Diabetic ketoacidosis (DKA) is the most common acute hyperglycaemic emergency in people with diabetes. DKA most often occurs in people with type 1 diabetes, but can also occur in patients with poorly controlled type 2 diabetes under stressful conditions. 1 Studies have reported an increased prevalence of DKA in patients with type 1 or type 2 diabetes with COVID-19 infection. Patients admitted to hospital with severe hyperglycaemia and DKA with COVID-19 infection have been shown to have increased severity of complications and a higher rate of mortality compared with patients without COVID-19. 2The Article by Shivani Misra and colleagues3 examined the incidence of emergency hospital admissions coded with DKA in a country-wide database in England. The study focused on three discrete time periods during the COVID-19 pandemic: from March 1 to June 30, 2020 (first wave), July 1 to Oct 31, 2020 (post-first wave), and Nov 1, 2020, to Feb 28, 2021 (second wave), and compared the incidence of DKA admissions during these periods with the mean incidence during the equivalent time periods in the 3 years before the