Program report: GENECOUNTING support programs
Program report: GENECOUNTING support programs
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DOI：
10.1111/j.1529-8817.2005.00225.x
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发表时间：
2006-03-01
影响因子：
1.9
通讯作者：
Sham, PC
中科院分区：
文献类型：
--
作者：
Curtis, D;Knight, J;Sham, PC
我们描述了一套增强GENECOUNTING可用性的程序，GENECOUNTING是一个用于估计不相关受试者单倍型频率的程序。这些程序被称为RUNGC、SCANASSOC、COMPGR、SCAN-GROUP和LDPAIRS，它们执行似然比测试和排列测试，以检测病例和对照之间或预定义组之间单倍型频率的差异，并输出数据集中所有标记对之间可能的单倍型分配和连锁不平衡统计表。
We describe a Suite of programs which enhance the usability of GENECOUNTING, a program for estimating haplotype frequencies in unrelated subjects. The programs, called RUNGC, SCANASSOC, COMPGR, SCAN-GROUP and LDPAIRS, carry out likelihood ratio tests and permutation tests to detect differences in haplotype frequencies between cases and controls,or between predefined groups, and output likely haplotype assignments and tables of linkage disequilibrium statistics between all pairs of markers in a dataset.