Asthma status moderates the relationship between neighbourhood disadvantage and obesity in African American adolescent females.
Asthma status moderates the relationship between neighbourhood disadvantage and obesity in African American adolescent females.
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哮喘状况调节了非裔美国青春期女性的邻里劣势与肥胖之间的关系。
DOI：
10.1002/osp4.370
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发表时间：
2019
影响因子：
2.2
通讯作者：
Sothern
中科院分区：
文献类型：
--
作者：
Cahill,LauraM;Fisher,KivaA;Robinson,WilliamT;Beiter,KaylinJ;Zabaleta,Jovanny;Tseng,TungS;Kepper,MauraM;Skizim,MegK;Griffiths,LaurenA;Uddo,RobertB;Pelligrino,NicoleE;Maronge,JacobM;Happel,Kyle;Scribner,Richard;Sothern
非洲裔美国青年在哮喘和肥胖方面存在显著的健康差异。成功的干预措施为解决这些差异提供了机会，但需要进行详细的研究，以确保其普遍性。这项研究调查了肥胖、邻里劣势和哮喘之间的关系。方法选取年龄在13 ~ 19岁（平均15.6岁[SD = 1.9]）的129名非裔美国女性。肥胖是通过体重指数（BMI）来衡量的。哮喘状况基于临床诊断和/或儿童期间哮喘和过敏国际研究（ISAAC）问卷调查的结果。集中劣势指数（CDI）评价邻里劣势。结果21.5% （n = 28）的参与者临床定义为哮喘，76.2% （n = 99）为肥胖，24.9% （n = 31）为非肥胖。平均BMI为35.1 (SD = 9.1)，平均CDI为1.0 （SD = 0.9）。CDI和肥胖在没有哮喘的参与者中显著相关，但在有哮喘的参与者中没有。多变量线性回归结果显示CDI与哮喘之间存在显著的交互作用（tvalue = 2.2，P= .03）。综上所述，本研究结果发现哮喘调节了邻里劣势与肥胖之间的关系。
IntroductionSignificant health disparities exist in asthma and obesity for African American youths. Successful interventions present an opportunity to address these disparities but require detailed study in order to ensure generalizability. This study investigated the intersection of obesity, neighbourhood disadvantage, and asthma.MethodsData were extracted from 129 African American females ages 13 to 19 years (mean = 15.6 years [SD = 1.9]). Obesity was measured via body mass index (BMI). Asthma status was based on clinical diagnosis and/or results of the International Study of Asthma and Allergies during Childhood (ISAAC) questionnaire. The concentrated disadvantage index (CDI) assessed neighbourhood disadvantage.ResultsFindings showed that 21.5% (n = 28) of participants were clinically defined as having asthma, 76.2% (n = 99) had obesity, and 24.9% (n = 31) were classified without obesity. The mean BMI was 35.1 (SD = 9.1) and the mean CDI was 1.0 (SD = 0.9). CDI and obesity were significantly associated in participants without asthma, but not in those with asthma. Multivariable linear regression results showed a significant interaction between CDI and asthma (tvalue = 2.2,P= .03).ConclusionIn sum, results from this study found that asthma moderated the relationship between neighbourhood disadvantage and obesity.