SnCl4-Catalyzed Aza-Acetalization of Aromatic Aldehydes: Synthesis of Aryl Substituted 3,4-Dihydro-2H-1,3-benzoxazines
SnCl4-Catalyzed Aza-Acetalization of Aromatic Aldehydes: Synthesis of Aryl Substituted 3,4-Dihydro-2H-1,3-benzoxazines
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DOI：
10.1080/00397911.2010.540691
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发表时间：
2012-01
影响因子：
2.1
通讯作者：
Zi-long Tang;Weiwen Chen;Zhonghua Zhu;Hanwen Liu
中科院分区：
文献类型：
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作者：
Zi-long Tang;Weiwen Chen;Zhonghua Zhu;Hanwen Liu
摘要四氯化锡是芳香醛与邻芳氨基甲基苯酚偶氮缩合反应的高效Lewis酸催化剂，在温和的反应条件下合成了一系列新型芳基取代的3，4-二氢-2H-1，3-苯并恶嗪。SnCl4是一种比对甲苯磺酸、硫酸和三氯化铝更有效的催化剂。图形摘要
Abstract Stannic tetrachloride was an efficient Lewis acid catalyst for the aza-acetalization of aromatic aldehydes with o-arylaminomethyl phenols, and a series of novel aryl substituted 3,4-dihydro-2H-1,3-benzoxazines were prepared in good yields under mild conditions. SnCl4 was a more efficient catalyst for the reaction than p-toluenesulfonic acid, sulfuric acid, and aluminium chloride. GRAPHICAL ABSTRACT