Sources of contrast in confocal reflectance imaging

Sources of contrast in confocal reflectance imaging
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DOI:
10.1364/ao.35.003441
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发表时间:
1996-07-01
期刊:
影响因子:
1.9
通讯作者:
RichardsKortum, R
RichardsKortum, R
中科院分区:
工程技术4区
文献类型:
--
作者:
Dunn, AK;Smithpeter, C;RichardsKortum, R

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研究了共焦成像中光学特性和图像对比度之间的关系。蒙特卡罗模拟已被开发用于分析三层介质中散射、折射率和吸收变化的影响。根据组织光学特性变化的计算信号与背景比计算对比度。结果表明,对比度的最大来源是折射率的变化。 (C) 1996 美国光学学会
The relationship between optical properties and image contrast in confocal imaging is investigated. A Monte Carlo simulation has been developed to analyze the effects of changes in scattering, index of refraction, and absorption in a three-layer medium. Contrast was calculated from the computed signal-to-background ratios for changes in tissue optical properties. Results show that the largest source of contrast is changes in refractive index. (C) 1996 Optical Society of America