Sources of contrast in confocal reflectance imaging
Sources of contrast in confocal reflectance imaging
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DOI:
10.1364/ao.35.003441
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发表时间:
1996-07-01
期刊:
影响因子:
1.9
通讯作者:
RichardsKortum, R
中科院分区:
文献类型:
--
作者:
Dunn, AK;Smithpeter, C;RichardsKortum, R
The relationship between optical properties and image contrast in confocal imaging is investigated. A Monte Carlo simulation has been developed to analyze the effects of changes in scattering, index of refraction, and absorption in a three-layer medium. Contrast was calculated from the computed signal-to-background ratios for changes in tissue optical properties. Results show that the largest source of contrast is changes in refractive index. (C) 1996 Optical Society of America