Left hemispheric α band cerebral oscillatory changes correlate with verbal memory.
Left hemispheric α band cerebral oscillatory changes correlate with verbal memory.
复制标题
左半球α带脑振荡变化与言语记忆相关。
DOI：
10.1038/s41598-020-72087-3
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Hirata M.
中科院分区：
文献类型：
--
作者：
Araki T;Watanabe Y;Hirata M.
通过脑磁图（MEG），在语言优势半球观察到事件相关同步（ERS）和事件相关去同步化（ERD）。然而，ERS/ERD和临床语言指标之间的关系尚不清楚。因此，本研究评估了36名受试者在动词生成任务中使用MEG的脑活动，并确定了θ，α，β，低γ和高γ频段的ERS/ERD功率值。临床语言指标采用韦氏记忆量表修订版。在双侧枕叶至左中央脑区的α带、双侧枕叶至左额区的β带和左额区的低γ带中观察到高功率信号。在双侧额区θ带和枕区高γ带也观察到ERS。此外，我们发现左侧中央后回和内侧上级额回的α-波段ERD功率与言语记忆得分之间存在显著负相关（相关系数分别为-0.574和-0.597）。这些结果表明，语言记忆力较低的个体具有较少的去分裂α-带ERD功率，左半球的α-带ERD功率可能是言语记忆的神经生理学生物标志物。
Event-related synchronisation (ERS) and event-related desynchronisation (ERD) have been observed via magnetoencephalography (MEG) in the language-dominant hemisphere. However, the relationship between ERS/ERD and clinical language indices is unclear. Therefore, the present study evaluated brain activity utilising MEG during a verb generation task in 36 subjects and determined ERS/ERD power values in θ, α, β, low γ and high γ frequency bands. To measure clinical language indices, we adopted Wechsler Memory Scale-revised. We observed ERD in the α band from the bilateral occipital to the left central brain region, in the β band from the bilateral occipital to the left frontal region and in the low γ band a high-power signal in the left frontal region. We also observed ERS in the θ band in bilateral frontal region and in the high γ band in bilateral occipital region. Furthermore, we found a significant negative correlation between α-band ERD power at the left postcentral gyrus and medial superior frontal gyrus and verbal memory score (correlation coefficients = − 0.574 and − 0.597, respectively). These results suggest that individuals with lower linguistic memory have less desynchronised α-band ERD power and α-band ERD power in the left hemisphere may be a neurophysiological biomarker for verbal memory.