Effects of unilateral naris occlusion on the olfactory eptihelium of adult mice
Effects of unilateral naris occlusion on the olfactory eptihelium of adult mice
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DOI：
10.1097/01.wnr.0000224762.54336.7d
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发表时间：
2006-07-31
期刊：
影响因子：
1.7
通讯作者：
Moon, Cheil
中科院分区：
文献类型：
--
作者：
Suh, Kyung Shik;Kim, So Yeun;Moon, Cheil
感觉刺激是神经元功能的重要组成部分，包括信息处理、树突和轴突细化、突触可塑性和神经元存活。我们研究了感觉神经元在嗅觉作为模型系统中的作用。通过单侧鼻孔阻塞阻塞感觉刺激导致嗅觉上皮细胞增殖下调和凋亡上调。因此，感觉刺激在维持成年嗅上皮的稳态中是重要的。因此，感觉刺激在维持成年嗅上皮的稳态中是重要的。我们的研究有助于进一步了解感觉刺激在出生后神经元发育中的作用和机制，以及复发性鼻塞患者的损伤和潜在治疗。
Sensory stimulation is an essential component of neuronal functions, including information processing, dendritic and axonal refinement, synaptic plasticity, and neuronal survival. We examined the roles of sensory neurons in the olfactory as the model system. Obstruction of sensory stimulation through unilateral naris occlusion caused downregulation of proliferation and upregulation of apoptosis of neurons in the olfactory epithelium. Sensory stimulation is therefore important in maintaining homeostasis in the adult olfactory epithelium. Sensory stimulation is therefore important in maintaining homeostasis in the adult olfactory epithelium. Our study contributes to further understanding the roles and mechanisms of sensory stimulation in the postnatal neuronal development as well as to the damage and potential treatments of patients who suffer recurrent nasal obstruction.