Case of metastatic pulmonary carcinoma in optic disc diagnosed from results of biopsy performed during vitrectomy surgery
Case of metastatic pulmonary carcinoma in optic disc diagnosed from results of biopsy performed during vitrectomy surgery
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DOI：
10.1007/s00417-011-1770-1
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发表时间：
2011-12-01
影响因子：
2.7
通讯作者：
Kaburaki, Toshikatsu
中科院分区：
文献类型：
--
作者：
Fukuda, Reina;Tanabe, Tatsuro;Kaburaki, Toshikatsu
眼内转移性肿瘤大多发生在葡萄膜，而孤立性转移到视神经很少被发现。我们报告一例原发性肺癌转移到视盘，通过玻璃体切除术中获得的活检结果进行诊断。一名69岁男性由于从视盘延伸到玻璃体腔的乳白色白色肿瘤而表现为逐渐的视力障碍。全身检查发现原发性鳞状细胞肺癌，在玻璃体切除术中从视盘肿瘤中获得活检标本，诊断为肺癌转移。尽管接受化学治疗及放射线治疗，患者仍死于脑转移。很少有继发性视盘肿瘤的报告，病理切片检查结果也很罕见。当观察到从视盘延伸出的乳白色白色肿瘤时，可能的鉴别诊断是转移性肿瘤。
Most intraocular metastatic tumors occur in the uveal tract, while isolated metastasis to the optic nerve is rarely found. We report a case of metastasis to the optic disc from primary lung cancer, diagnosed from biopsy findings obtained during a vitrectomy.A 69-year-old male presented with gradual visual impairment due to a milky white tumour that extended from the optic disc into the vitreous cavity. A systemic examination revealed primary squamous cell lung cancer.A biopsy specimen was obtained from the optic disc tumor during a vitrectomy, which led to a diagnosis of metastasis from lung cancer. Despite courses of chemotherapy and radiotherapy, the patient died of brain metastasis.There are few reports of secondary optic disc tumors and pathological biopsy findings are rare. When a milky white tumor is observed extending from the optic disc, a possible differential diagnosis is metastatic neoplasm.