Trinuclear intermediate in the copper-mediated reduction of O-2: Four electrons from three coppers
Trinuclear intermediate in the copper-mediated reduction of O-2: Four electrons from three coppers
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DOI：
10.1126/science.273.5283.1848
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发表时间：
1996-09-27
期刊：
影响因子：
56.9
通讯作者：
Stack, TDP
中科院分区：
文献类型：
--
作者：
Cole, AP;Root, DE;Stack, TDP
金属配合物与二氧（O-2）的反应通常以1:1、2:1或4:1（金属：O-2）的化学计量进行。提出了一种离散的、结构特征为3:1的产品。这种混合价三核铜簇，含有高度氧化的三价氧化态铜，表现出O-2键断裂和有趣的结构、光谱和氧化还原性质。讨论了该合成配合物与多铜氧化酶三核活性位点O-2还原的相关性。
The reaction of metal complexes with dioxygen (O-2) generally proceeds in 1:1, 2:1, or 4:1 (metal:O-2) stoichiometry. A discrete, structurally characterized 3:1 product is presented. This mixed-valence trinuclear copper cluster, which contains copper in the highly oxidized trivalent oxidation state, exhibits O-2 bond scission and intriguing structural, spectroscopic, and redox properties. The relevance of this synthetic complex to the reduction of O-2 at the trinuclear active sites of multicopper oxidases is discussed.