Empathy and symptoms dimensions of patients with obsessive-compulsive disorder
Empathy and symptoms dimensions of patients with obsessive-compulsive disorder
复制标题
DOI：
10.1016/j.jpsychires.2008.05.007
复制
发表时间：
2009-01-01
影响因子：
4.8
通讯作者：
Moll, Jorge
中科院分区：
文献类型：
--
作者：
Fontenelle, Leonardo F.;Soares, Isabela D.;Moll, Jorge
强迫症(OCD)患者经常表现出的认知和/或行为很可能反映出他们对不同环境因素，包括他们的子女、家庭成员、神圣实体，甚至是无生命的物体存在“超依恋”。基于强迫症症状和生理人际依恋机制都涉及重叠的额叶-边缘腹侧回路这一事实，我们假设共情(用人际反应指数(IRI)评估)与强迫症症状维度之间存在关系。我们对53名强迫症患者和53名来自社区的年龄和性别匹配的人进行了评估，包括结构化的诊断DSM-IV轴障碍的临床访谈，修订的储蓄问卷，IRI(由四个子量表组成)，强迫-强迫问卷修订，Beck抑郁问卷和Beck焦虑问卷。与社区对照组相比，强迫症患者表现出更多的情感移情(即移情关怀(p=0.006)和个人不适(p<；0.001))。在双变量分析中，强迫症患者囤积症状的严重程度与共情关怀(r=0.39；p<；0.001)、幻想(r=0.36；p<；0.01)和个人不适(r=0.39；p<；0.001)相关。在对抑郁和焦虑共病进行调整的偏相关分析中，只有囤积和幻想之间的关联仍然很强(r=0.41p<；0.001)。一个包括囤积、抑郁和焦虑症状严重程度的模型预测了幻想量表的33%的变异。我们的发现表明，囤积与人际反应的特定方面有关。然而，抑郁和焦虑并存，解释了强迫症患者表现出的很大一部分同理心特征。(C)2008爱思唯尔有限公司。保留所有权利。
Patients with obsessive-compulsive disorder (OCD) often display cognitions and/or behaviors that may well reflect the existence of "hyper-attachment" to different environmental elements, including their offspring, family members, divine entities, or even inanimate objects. Based on the fact that both OCD symptoms and physiologic interpersonal attachment mechanisms involve overlapping ventral fronto-limbic circuits, we hypothesized that there is a relationship between empathy, evaluated with the Interpersonal Reactivity Index (IRI), and OCD symptom dimensions. We evaluated 53 patients with OCD and 53 age- and sex-matched individuals from the community with the Structured Clinical Interview for the Diagnosis of DSM-IV axis I disorders, the Saving Inventory-Revised, the IRI (composed of four sub-scales), the Obsessive-Compulsive Inventory - Revised, the Beck Depression Inventory, and the Beck Anxiety Inventory. Patients with OCD displayed greater levels of affective empathy (i.e., empathic concern (p = 0.006) and personal discomfort (p < 0.001)) than community controls. In bivariate analyses, the severity of hoarding symptoms of patients with OCD correlated with empathic concern (r = 0.39; p < 0.001), fantasy (r = 0.36; p < 0.01), and personal discomfort (r = 0.39; p < 0.001). In partial correlation analyses adjusting for comorbid depression and anxiety, only the association between hoarding and fantasy remained robust (r = 0.41; p < 0.001). A model that included severity of hoarding, depression, and anxiety symptoms predicted 33% of the variance oil the fantasy scale. Our findings suggest that hoarding is linked to specific aspects of interpersonal reactivity. Comorbid depression and anxiety, however, explain a large proportion of the empathic profile exhibited by patients with OCD. (C) 2008 Elsevier Ltd. All rights reserved.