Serotonin release as a possible mechanism of reserpine action.
Serotonin release as a possible mechanism of reserpine action.
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血清素释放是利血平作用的可能机制。
DOI：
10.1126/science.122.3165.374
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发表时间：
1955
期刊：
影响因子：
56.9
通讯作者：
B. Brodie
中科院分区：
文献类型：
--
作者：
A. Pletscher;P. A. Shore;B. Brodie
5-羟色胺释放作为利血平作用的可能机制先前的通讯报道了利血平（一种镇静剂）和5-羟色胺（一种被认为在脑功能中起作用的物质）在生理作用上的某些相似性(1)。这两种化合物在小鼠中都显示出镇静作用，并通过中枢机制增强某些催眠药物的作用(2)。poten -
Serotonin Release as a Possible Mechanism of Reserpine Action Previous communications have re-ported certain similarities in thephysio-logic actions of reserpine, a tranquillizing agent, and serotonin (5-hydroxytrypta-mine), a substance postulated to have a role in brain function (1). Both com-pounds show sedative effects in mice and potentiate the action of certain hypnotics by a central mechanism (2). The poten-