DICTYOSTELIUM-DISCOIDEUM - A MODEL SYSTEM FOR CELL-CELL INTERACTIONS IN DEVELOPMENT
DICTYOSTELIUM-DISCOIDEUM - A MODEL SYSTEM FOR CELL-CELL INTERACTIONS IN DEVELOPMENT
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DOI：
10.1126/science.2672337
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发表时间：
1989-09-08
期刊：
影响因子：
56.9
通讯作者：
DEVREOTES, P
中科院分区：
文献类型：
--
作者：
DEVREOTES, P
细胞黏菌Dictyosteelium discoideum经历了从单细胞变形虫到多细胞有机体的转变，这是其生命周期的一个自然部分。一种控制趋化性、形态发生和基因表达的细胞-细胞信号传导方法已经在这种生物体中发展起来，对这种信号传导系统的详细了解为后生动物发育中的细胞间通讯机制提供了线索。
The cellular slime moldDictyostelium discoideumundergoes a transition from single-celled amoebae to a multicellular organism as a natural part of its life cycle. A method of cell-cell signaling that controls chemotaxis, morphogenesis, and gene expression has developed in this organism, and a detailed understanding of this signaling system provides clues to mechanisms of intercellular communication in the development of metazoans.