Effects of UV Treatment on Ceria-Stabilized Zirconia/Alumina Nanocomposite (NANOZR)
Effects of UV Treatment on Ceria-Stabilized Zirconia/Alumina Nanocomposite (NANOZR)
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DOI：
10.3390/ma13122772
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发表时间：
2020-06-01
期刊：
影响因子：
3.4
通讯作者：
Okazaki, Joji
中科院分区：
文献类型：
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作者：
Komasa, Satoshi;Takao, Seiji;Okazaki, Joji
纳米结构氧化锆/氧化铝复合材料（NANOZR）已被探索作为一种合适的材料，用于制造植入物的患者与金属过敏。在这项研究中，我们研究了UV处理对NANOZR表面的影响。实验组为UV处理的NANOZR，对照组为未处理的NANOZR。对紫外光处理后的材料表面的观察表明，没有机械或结构的变化，但材料表面的碳含量减少，材料表面显示出超亲水性。此外，研究了NANOZR板的UV诱导的超亲水性对各种细胞的粘附行为的影响。NANOZR表面的处理被发现，以促进蛋白质吸附到it. In体外评价使用大鼠骨髓细胞，人血管内皮细胞，大鼠牙周膜细胞显示高水平的粘附在实验组。此外，明确了NANOZR表面形成活性氧并抑制氧化应激的产生。总体而言，研究结果表明，UV处理的NANOZR可用作新型陶瓷植入物材料。
Nanostructured zirconia/alumina composite (NANOZR) has been explored as a suitable material for fabricating implants for patients with metal allergy. In this study, we examined the effect of UV treatment on the NANOZR surface. The experimental group was UV-treated NANOZR and the control group was untreated NANOZR. Observation of the surface of the UV-treated materials revealed no mechanical or structural change; however, the carbon content on the material surface was reduced, and the material surface displayed superhydrophilicity. Further, the effects of the UV-induced superhydrophilic properties of NANOZR plates on the adhesion behavior of various cells were investigated. Treatment of the NANOZR surface was found to facilitate protein adsorption onto it. An in vitro evaluation using rat bone marrow cells, human vascular endothelial cells, and rat periodontal ligament cells revealed high levels of adhesion in the experimental group. In addition, it was clarified that the NANOZR surface forms active oxygen and suppresses the generation of oxidative stress. Overall, the study results suggested that UV-treated NANOZR is useful as a new ceramic implant material.