User attitudes in analyzing digital slides in a quality control test bed: A preliminary study
User attitudes in analyzing digital slides in a quality control test bed: A preliminary study
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DOI：
10.1016/j.cmpb.2006.02.011
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发表时间：
2006-05-01
影响因子：
6.1
通讯作者：
Beltrami, Carlo Alberto
中科院分区：
文献类型：
--
作者：
Della Mea, Vincenzo;Demichelis, Francesca;Beltrami, Carlo Alberto
病理学家通过明视野显微镜检查适当染色的载玻片，以便通过观察组织和细胞进行组织病理学或细胞病理学诊断。载玻片可作为病人疾病的永久记录。在患者的治疗过程中，在治疗开始之前，可能需要在其他机构审查载玻片。由于其易碎的性质，理想的是载玻片的可运输的永久数字传真。数字载玻片是表示病理学家通常使用的整个载玻片或其重要部分的一组数字图像;它通常由大量的图像组成，多达数千个，这使得它的管理困难。本文件提供了复制载玻片所需的要求和可用的技术设备的描述，然后介绍了我们在不同硬件上实现的两个系统的特点，以及数字幻灯片浏览器的特点。在两个实验测试阶段中对查看器进行了评估，在此期间测量了用户行为和诊断报告。在两个实验中使用的数字载玻片用任一系统获得。数字幻灯片的可能应用进行了讨论，包括本科和专业教育，质量控制，以及对全样本的图像分析，以及组织微阵列。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
The pathologist examines suitably stained glass slides through a bright field microscope in order to render histopathological or cytological diagnosis by looking at tissues and cells. Glass slides serve as a permanent record of the patient disease. Over the course of a patient's treatment slides may need to be reviewed at other institutions before treatment can commence. Due to their fragile nature a transportable permanent digital facsimile of the glass slide would be ideal.A digital slide is a set of digital images representing the whole slide normally used by the pathologist, or a significant part of it; it is usually made by a large amount of images, up to thousands, which makes its management difficult.The present paper provides a description of the requirements needed to reproduce glass slides and of the available technological equipments, then the features of the two systems we implemented on different hardware are described, together with those of the digital slide viewer. The viewer was evaluated in two experimental test phases, during which user behaviour and diagnostic reports were measured. Digital slides used in the two experiments were acquired with either system. Possible applications of digital slides are then discussed, including undergraduate and professional education, quality control, and image analysis on full samples as well as on tissue microarrays. (c) 2006 Elsevier Ireland Ltd. All rights reserved.