Chiral Amplification in Double-Stranded Helical Polymers through Chiral and Achiral Amidinium-Carboxylate Salt Bridges
Chiral Amplification in Double-Stranded Helical Polymers through Chiral and Achiral Amidinium-Carboxylate Salt Bridges
复制标题
通过手性和非手性脒-羧酸盐桥实现双链螺旋聚合物的手性扩增
DOI：
10.1038/pj.2012.70
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
and E. Yashima
中科院分区：
文献类型：
--
作者：
W. Makiguchi;S. Kobayashi;Y. Furusho;and E. Yashima
A series of m-terphenyl-based random copolymers of chiral and achiral amidines, and their complementary homopolymers of achiral carboxylic acids were prepared by the copolymerization of a p-diiodobenzene derivative, with the diethynyl monomers containing a chiral or achiral amidine group and a carboxyl group using the Sonogashira coupling reaction. The obtained chiral/achiral amidine copolymers assembled into a double-stranded helical structure upon complexation with the complementary achiral homopolymer of carboxylic acids through interstrand amidinium− carboxylate salt bridges. The complexes exhibited characteristic induced cotton effects in the π-conjugated main-chain chromophore regions, indicating that the interstrand duplexes possess a preferred-handed double-helical structure. The effect of the chiral and achiral amidine contents on the amplification of the helical chirality (‘the sergeants and soldiers effect’) during the interstrand double-helix formation was investigated by comparing the cotton effect patterns and intensities of the duplexes with those of the corresponding all-chiral amidine-based double-helical polymer.
