Phospholipid biosynthesis in yeast.
Phospholipid biosynthesis in yeast.
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DOI：
10.1146/annurev.bi.58.070189.003223
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发表时间：
1989
影响因子：
16.6
通讯作者：
G. Carman;S. A. Henry
中科院分区：
文献类型：
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作者：
G. Carman;S. A. Henry
介绍636酵母中磷脂代谢途径636酵母中磷脂代谢酶CDp·DG合成酶639 PS合成酶640 PI合成酶642 PI激酶的纯化及性质643 I·I·P合酶的纯化和性质644酵母中磷脂生物降解酶的调节645水溶性磷脂前体对磷脂生物合成酶表达的调节645生长阶段对磷脂生物合成酶表达的调节....... ....... . .. . , ....... 647 PS合成酶活性的调节648酵母中磷脂合成的遗传学649结构基因突变体“，....... 650个磷脂合成调控缺陷突变体656酵母细胞对磷脂的需求.... . 657酵母磷脂合成的分子生物学....... 659结构基因的分离与分析659转录调控661什么样的代谢信号参与磷脂合成的协调调控？662结论和总结667
INTRODUCTION 636 PHOSPHOLIPID BIOSYNTHETIC PATHWAYS IN YEAST 636 PHOSPHOLIPID BIOSYNTHETIC ENZYMES PURIFIED FROM YEAST 637 Purification and Properties of CDp·DG Synthase 639 Purification and Properties of PS Synthase 640 Purification and Properties of PI Synthase 642 Purification and Properties of PI Kinase...... 643 Purification and Properties of I·I·P Synthase 644 REGULATION OF PHOSPHOLIPID BIOSYNTHETIC ENZYMES IN yEAST ....... 645 Regulation of Expression of Phospholipid Biosynthetic Enzymes by Water· Soluble Phospholipid Precursors 645 Regulation of Expression of Phospholipid Biosynthetic Enzymes by the Growth Phase ........ ....... ....... . .. . , ....... 647 Regulation of PS Synthase Activity 648 GENETICS OF PHOSPHOLIPID SYNTHESIS IN YEAST 649 Structural Gene Mutants """"' " , ....... 650 Mutants with Defects in the Regulation of Phospholipid Synthesis 656 Phospholipid Requirements of Yeast Cells ..... .... . 657 MOLECULAR BIOLOGY OF PHOSPHOLIPID SYNTHESIS IN YEAST ....... ....... 659 Isolation and Analysis of Structural Genes ".. 659 Transcriptional Regulation 661 What Melabolic Signals are Involved in the Coordinate Regulation of Phospholipid Synthesis? 662 CONCLUSIONS AND SUMMARY 667