Electron microscopic study of reticulohistiocytoma. An unusual case of congenital, self-healing reticulohistiocytosis.
Electron microscopic study of reticulohistiocytoma. An unusual case of congenital, self-healing reticulohistiocytosis.
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网状组织细胞瘤的电子显微镜研究。
作者：
K. Hashimoto;M. Pritzker
1例先天性皮肤多中心性网状组织细胞瘤随访1年多。所有病变均在31/2个月内消失，无复发。电镜检查显示典型的组织细胞增生。特征性地，大多数肿瘤细胞含有许多致密体，其中许多显示髓鞘样层状结构。约10%的肿瘤细胞含有朗格汉斯细胞颗粒。其中一些细胞还含有有髓鞘致密体。这些特征在组织细胞增生症X的朗格汉斯细胞中并不常见，并且疾病的良性过程被强调为该实体与组织细胞增生症X的鉴别点。没有细胞表现出类似神经节细胞。
One case of congenital, multicentric reticulohistiocytoma of the skin was followed up for more than a year. All lesions disappeared within 31/2 months, and there was no recurrence. Electron microscopic examination revealed typical histiocytic proliferation. Characteristically, the majority of the tumor cells contained numerous dense bodies, many of which showed myelin-like laminations. About 10% of the tumor cells contained Langerhans' cell granules. Some of these cells also contained myelinated dense bodies. These features, which are not commonly seen in Langerhans' cells of histiocytosis X, and the benign course of the disease were emphasized as differentiating points of this entity from histiocytosis X. No cell exhibited a resemblance to ganglioneuronal cells.