EFFECTS OF INTRAVENOUS-INJECTION OF BCG OR FREUND COMPLETE ADJUVANT ON SWINE ALVEOLAR MACROPHAGES
EFFECTS OF INTRAVENOUS-INJECTION OF BCG OR FREUND COMPLETE ADJUVANT ON SWINE ALVEOLAR MACROPHAGES
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DOI：
10.1016/0165-2427(83)90006-5
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发表时间：
1983-01-01
影响因子：
1.8
通讯作者：
LECLERC, C
中科院分区：
文献类型：
--
作者：
CHARLEY, B;PETIT, E;LECLERC, C
The i.v. injection of killed mycobacteria in oil (Freund''s complete adjuvant) or BCG produces an accumulation of macrophages in swine alveolar airspaces. The collected alveolar macrophages were studied in vitro; expression of Fc and complement surface receptors, uptake of chicken red blood cells and in vitro spreading were not modified by either treatment; the tumor cytostatic activity of alveolar macrophages decreased following administration of high doses of BCG or adjuvant. These treated cells had a lower thymidine incorporation rate, which suggest that cell accumulation is related to an influx of blood monocytes and not to an in situ cell multiplication.
