Prefrontal activity predicts monkeys' decisions during an auditory category task.
Prefrontal activity predicts monkeys' decisions during an auditory category task.
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DOI：
10.3389/neuro.07.016.2009
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发表时间：
2009
影响因子：
3.5
通讯作者：
Cohen YE
中科院分区：
文献类型：
--
作者：
Lee JH;Russ BE;Orr LE;Cohen YE
将听觉分类与目标导向行为（如决策）相关的神经相关性尚未得到很好的理解。由于前额叶皮层（PFC）在执行功能和听觉对象的分类中起着重要的作用，我们假设PFC中的神经活动应该预测动物在类别任务中的行为报告（决策）。为了验证这一假设，我们测试了在猴子对人类口语进行分类时记录的PFC活动（Russ等人，）。我们发现腹外侧前额叶皮层的活动，平均来说，与猴子的选择相关性最好，而不是与听觉刺激相关。这一发现表明，在非空间听觉任务的PFC活动和行为选择之间的直接联系。
The neural correlates that relate auditory categorization to aspects of goal-directed behavior, such as decision-making, are not well understood. Since the prefrontal cortex (PFC) plays an important role in executive function and the categorization of auditory objects, we hypothesized that neural activity in the PFC should predict an animal's behavioral reports (decisions) during a category task. To test this hypothesis, we tested PFC activity that was recorded while monkeys categorized human spoken words (Russ et al.,). We found that activity in the ventrolateral PFC, on average, correlated best with the monkeys' choices than with the auditory stimuli. This finding demonstrates a direct link between PFC activity and behavioral choices during a non-spatial auditory task.