Nanomechanical properties and molecular structures of in vitro mineralized tissues on anodically oxidized titanium surfaces.
Nanomechanical properties and molecular structures of in vitro mineralized tissues on anodically oxidized titanium surfaces.
复制标题
阳极氧化钛表面体外矿化组织的纳米力学特性和分子结构。
DOI：
10.1016/j.nano.2013.09.007
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发表时间：
2014
期刊：
影响因子：
5.5
通讯作者：
T.
中科院分区：
文献类型：
--
作者：
Jang;I-. K.;Tanaka;R.;Wurihan;Suzuki;D.;Shibata Y.;Fujisawa;N.;Tanimoto;Y.;Ogura;K.;Kamijo;R.;Miyazaki;T.
种植体表面与骨组织界面矿化组织的生物力学稳定性至关重要。在氯化物溶液中制备的阳极氧化钛可以增强粘附性成骨细胞的矿化，并对口腔微生物具有抗菌活性。我们评估了在氯化物溶液中阳极氧化钛表面前后形成的体外矿化组织的纳米机械性能和分子结构。阳极氧化的钛表面表现出比热氧化和裸露的钛表面更强的成骨基因表达。氯化物中阳极氧化钛的制备增强了其周围矿化组织的产生。然而，在没有氯化物的情况下，阳极氧化钛周围的矿化组织增加了矿物：基质和交联率，导致更高的硬度和更低的弹性。从临床编辑的角度来看，本研究使用阳极氧化钛来提高种植体表面-骨组织界面矿化组织的生物力学稳定性。未加氯化物的阳极氧化钛周围的矿化组织增加了矿物与基质的比例和交联度，导致较高的硬度和较低的弹性。
The biomechanical stability of mineralized tissues at the interface between implant surface and bone tissue is of critical importance. Anodically oxidized titanium prepared in a chloride solution results in enhanced mineralization of adherent osteoblasts and has antimicrobial activity against oral microorganisms. We evaluated the nanomechanical properties and molecular structures of the in vitro mineralized tissues developing around anodically oxidized titanium surfaces with and without preparation in chloride solution. Anodically oxidized titanium surfaces showed superior osteogenic gene expressions than those of thermally oxidized and bare titanium surfaces. Preparation of anodically oxidized titanium in chloride enhanced the production of mineralized tissue around it. However, the mineralized tissue around anodically oxidized titanium prepared without chloride had increased mineral:matrix and cross-linking ratios, resulting in higher hardness and lower elasticity.From the Clinical EditorIn this study anodically oxidized titanium was used to enhance the biomechanical stability of mineralized tissues at the implant surface -- bone tissue interface. The mineralized tissue around anodically oxidized titanium prepared without chloride had increased mineral:matrix and cross-linking ratios, resulting in higher hardness and lower elasticity.