Lennox-Gastaut syndrome: A consensus approach to differential diagnosis

Lennox-Gastaut syndrome: A consensus approach to differential diagnosis
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DOI:
10.1111/epi.12567
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发表时间:
2014-10-01
期刊:
影响因子:
5.6
通讯作者:
Sankar, Raman
Sankar, Raman
中科院分区:
医学1区
文献类型:
--
作者:
Bourgeois, Blaise F. D.;Douglass, Laurie M.;Sankar, Raman

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Lennox-Gastaut 综合征 (LGS) 是一种严重的癫痫性脑病,具有其他难治性儿童癫痫的许多特征和特点。准确和早期诊断对于预后和整体患者管理至关重要。然而,LGS 的准确诊断在临床上具有挑战性。本文总结了 LGS 的主要特征以及与其他儿童癫痫的重叠领域。根据 2012 年 6 月在伊利诺伊州芝加哥召开的 LGS 专家委员会的意见,作者强调了进行鉴别诊断的关键诊断测试,并为疑似 LGS 患者提出了诊断方案。
Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy that shares many features and characteristics of other treatment-resistant childhood epilepsies. Accurate and early diagnosis is essential to both prognosis and overall patient management. However, accurate diagnosis of LGS can be clinically challenging. This article summarizes key characteristics of LGS and areas of overlap with other childhood epilepsies. Drawing upon input from a committee of established LGS experts convened in June 2012 in Chicago, Illinois, the authors highlight key diagnostic tests for making the differential diagnosis and propose a diagnostic scheme for people with suspected LGS.