Feedforward and feedback sources of choice probability in neural population responses.

Feedforward and feedback sources of choice probability in neural population responses.
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DOI:
10.1016/j.conb.2016.01.009
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发表时间:
2016-04
影响因子:
5.7
通讯作者:
Nienborg H
Nienborg H
中科院分区:
医学2区
文献类型:
--
作者:
Cumming BG;Nienborg H

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感觉神经元所携带的信号处理如何支持感知决策是神经科学中一个长期存在的问题。当清醒的动物在阈值附近执行心理物理任务时,记录其神经元活动的能力是研究这些问题的关键进展。感觉神经元的活动与动物报告的决定(“选择概率”)之间的试验与试验之间的相关性,即使是在重复呈现相同刺激的情况下进行测量,也为这个问题提供了见解。但是,理解感觉神经元和行为之间的这种共变性的来源已经被证明比最初出现的要困难得多。下面,我们讨论我们目前对这些相关性的理解。
How the processing of signals carried by sensory neurons supports perceptual decisions is a longstanding question in neuroscience. The ability to record neuronal activity in awake animals while they perform psychophysical tasks near threshold has been a key advance in studying these questions. Trial-to-trial correlations between the activity of sensory neurons and the decisions reported by animals (“choice probabilities”), even when measured across repeated presentations of an identical stimulus provide insights into this problem. But understanding the sources of such co-variability between sensory neurons and behavior has proven more difficult than it initially appeared. Below, we discuss our current understanding of what gives rise to these correlations.