Assisted Partner Services for People Who Inject Drugs: Index Characteristics Associated With Untreated HIV in Partners.
Assisted Partner Services for People Who Inject Drugs: Index Characteristics Associated With Untreated HIV in Partners.
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DOI：
10.1097/qai.0000000000003062
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发表时间：
2022-11-01
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辅助伙伴服务（APS）是一项可行、可接受和有效的战略，可提高艾滋病毒检测的接受程度；然而，在非洲注射毒品者（PWID）中，并没有广泛使用它来通知性伴侣和注射伴侣可能接触艾滋病毒并提供检测服务。肯尼亚的内罗毕、基利菲和蒙巴萨县。纳入感染艾滋病毒的PWID（指数），并要求提供性伴侣和注射伴侣的联系信息，追踪并提供艾滋病毒检测。通过访谈（NNTI）所需的指标数量来评估APS的效率，以找到一个不知道自己艾滋病毒状况或未接受抗逆转录病毒治疗的额外伴侣。我们定义了与更高效率相关的指数参与者特征，定义为较低的nnti。在783个指标中，识别一个不知道自己艾滋病毒状况的伴侣的NNTI为7.1，识别一个未接受抗逆转录病毒治疗的艾滋病毒阳性伴侣（无论状态意识如何）的NNTI为4.1。向977名伴侣提供了APS，并且在以下指标中更有效地识别未接受抗逆转录病毒治疗的伴侣（n=201）：女性（NNTI=2.9 vs. 5.7, p<0.001），不知道自己的艾滋病毒状况（NNTI=2.2 vs. 4.2, p=0.009），未接受抗逆转录病毒治疗（NNTI=2.1 vs. 4.9, p<0.001），未参加美沙酮计划（NNTI=3.3 vs. 10.4, p<0.001），报告注射时间<5年（NNTI=3.3 vs. 5.0, p=0.005），或来自内罗毕（NNTI=3.2 vs. 5.6, p<0.001）。在具有某些特征的艾滋病毒感染者中扩大APS可导致更有效的APS和更大的伙伴参与艾滋病毒护理。
Assisted partner services (APS) is a feasible, acceptable, and effective strategy that increases uptake of HIV testing; however, it has not been used widely among persons who inject drugs (PWID) in Africa to notify sexual and injecting partners of potential exposures to HIV and provide testing services. Nairobi, Kilifi, and Mombasa counties in Kenya. PWID living with HIV (indexes) were enrolled and asked to provide contact information for sexual and injecting partners who were traced and offered HIV testing. APS efficiency was assessed by the number of indexes needed to interview (NNTI) to find one additional partner who was unaware of their HIV status or not on ART. We defined index participant characteristics associated with greater efficiency, defined as lower NNTIs. Among 783 indexes, the NNTI to identify one partner unaware of their HIV status was 7.1 and to identify one HIV-positive partner not on ART (regardless of status awareness) was 4.1. APS was provided to 977 partners and was more efficient in identifying partners who were not on ART (n=201) among indexes who were female (NNTI=2.9 vs. 5.7, p<0.001), unaware of their HIV status (NNTI=2.2 vs. 4.2, p=0.009), not on ART (NNTI=2.1 vs. 4.9; p<0.001), not enrolled in a methadone program (NNTI=3.3 vs. 10.4, p<0.001), reported injecting <5 years (NNTI=3.3 vs. 5.0; p=0.005), or from Nairobi (NNTI=3.2 vs. 5.6, p<0.001). Scaling up APS among PWID living with HIV with certain characteristics could result in more efficient APS and greater partner engagement in HIV care.