Assembled Structures and Chiroptical Properties of Amphiphilic Block Copolymers Synthesized by RAFT Polymerization of N‐Acryloyl‐L‐alanine
Assembled Structures and Chiroptical Properties of Amphiphilic Block Copolymers Synthesized by RAFT Polymerization of N‐Acryloyl‐L‐alanine
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DOI：
10.1002/macp.200800254
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发表时间：
2008-10
影响因子：
2.5
通讯作者：
H. Mori;Motonobu Matsuyama;T. Endo
中科院分区：
文献类型：
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作者：
H. Mori;Motonobu Matsuyama;T. Endo
采用可逆加成-断裂链转移（RAFT）聚合法合成了具有手性和pH依赖性溶解性的两亲性氨基酸嵌段共聚物聚（N-丙烯酰-L-丙氨酸）、聚（A-Ala-OH）。A-Ala-OH的直接聚合没有任何保护化学使用二硫代氨基甲酸酯封端的聚苯乙烯或聚（N-丙烯酰基-L-苯丙氨酸甲酯）作为大链转移剂产生定义明确的两亲性嵌段共聚物。利用动态光散射、圆二色谱和紫外-可见光谱等方法研究了这类两亲性嵌段共聚物在选择性溶剂中的自组装行为和手性光学性质。
Amino acid-based amphiphilic block copolymers involving poly(N-acryloyl-L-alanine), poly(A-Ala-OH), which exhibits a characteristic chiroptical property and pH-dependent solubility, have been synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization. The direct polymerization of A-Ala-OH without any protecting chemistry using the dithiocarbamate-terminated polystyrene or poly(N-acryloyl-L-phenylalanine methyl ester) as a macrochain transfer agent produced well-defined amphiphilic block copolymers. The self-assembly behaviors and chiroptical properties of these amphiphilic block copolymers in selective solvents were investigated by dynamic light scattering, circular dichroism, and UV-Vis spectroscopic methods.