Heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia.
复制标题

DOI:
10.1182/asheducation-2013.1.668
复制
发表时间:
2013
期刊:
Hematology. American Society of Hematology. Education Program
影响因子:
--
通讯作者:
Arepally GM
Arepally GM
中科院分区:
其他
文献类型:
--
作者:
Lee GM;Arepally GM

文献摘要

参考文献

被引文献

相似文献

肝素诱导的血小板减少症(HIT)是一种由识别血小板因子4 (PF4)和肝素复合物的抗体引起的血栓性疾病。HIT常被认为是肝素治疗患者血小板减少症的鉴别诊断。HIT是一个具有挑战性的诊断,因为住院患者常规使用肝素,常见的血小板减少症,以及在接受肝素治疗的患者中抗pf4 /肝素血清转换率高。本章将通过强调临床和实验室评估的关键要素来总结我们对HIT的诊断方法。
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder caused by antibodies that recognize complexes of platelet factor 4 (PF4) and heparin. HIT is frequently considered in the differential diagnosis of thrombocytopenia occurring in patients on heparin therapy. HIT is a challenging diagnosis because of routine heparin use in hospitalized patients, the common occurrence of thrombocytopenia, and high rates of anti-PF4/heparin seroconversions in patients treated with heparin. This chapter will summarize our diagnostic approach to HIT by underscoring critical elements of the clinical and laboratory evaluation.
DOI: 10.1055/s-2004-831044
发表时间: 2004-06-01
影响因子: 5.7
作者:
Greinacher, A
通讯作者: Greinacher, A
DOI: 10.1056/nejmct1206642
发表时间: 2013-02-21
影响因子: 158.5
作者:
Kelton, John G.;Arnold, Donald M.;Bates, Shannon M.
通讯作者: Bates, Shannon M.
DOI: 10.1111/jth.12208
发表时间: 2013-06-01
影响因子: 10.4
作者:
Nazi, I.;Arnold, D. M.;Kelton, J. G.
通讯作者: Kelton, J. G.
DOI: 10.1002/jca.20289
发表时间: 2011-01-01
影响因子: 1.5
作者:
Jaben, Elizabeth A.;Torloni, A. Sergio;Winters, Jeffrey L.
通讯作者: Winters, Jeffrey L.
DOI: 10.1182/blood-2012-07-443051
发表时间: 2012-11-15
期刊: BLOOD
影响因子: 20.3
作者:
Cuker, Adam;Gimotty, Phyllis A.;Warkentin, Theodore E.
通讯作者: Warkentin, Theodore E.