Arabidopsis pentatricopeptide repeat protein SOAR1 plays a critical role in abscisic acid signalling.
Arabidopsis pentatricopeptide repeat protein SOAR1 plays a critical role in abscisic acid signalling.
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拟南芥五肽重复蛋白 SOAR1 在脱落酸信号传导中发挥关键作用
DOI：
10.1093/jxb/eru293
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发表时间：
2014-10
影响因子：
6.9
通讯作者：
Zhang DP
中科院分区：
文献类型：
--
作者：
Mei C;Jiang SC;Lu YF;Wu FQ;Yu YT;Liang S;Feng XJ;Portoles Comeras S;Lu K;Wu Z;Wang XF;Zhang DP
作者发现一种五肽重复（PPR）蛋白SOAR1是ABA信号传导的关键参与者，该蛋白定位于细胞质和细胞核，可能调节核基因的表达。从CHLH/ABAR[编码mg螯合酶H亚基/推定脱落酸（ABA）受体（ABAR）]过表达系中筛选ABAR过表达的显性抑制因子soar1-1D，以探索ABAR介导的ABA信号传导机制。SOAR1基因编码一种定位于细胞质和细胞核的五肽重复（PPR）蛋白。SOAR1的下调强烈增强了ABA应答，而上调则几乎完全损害了ABA应答，这表明SOAR1是ABA信号传导的一个关键的负调控因子。进一步的遗传证据支持SOAR1在ABAR下游起作用，并可能在aba应答转录因子ABI5的上游起作用。SOAR1表达的变化改变了包括ABI5在内的aba应答基因子集的表达。这些发现为进一步阐明PPR蛋白的功能机制和复杂的ABA信号网络提供了重要信息。
The authors identify a pentatricopeptide repeat (PPR) protein SOAR1 as a crucial player of ABA signalling, which localizes to both the cytosol and nucleus probably to regulate nuclear gene expression. A dominant suppressor of the ABAR overexpressor, soar1-1D, from CHLH/ABAR [coding for Mg-chelatase H subunit/putative abscisic acid (ABA) receptor (ABAR)] overexpression lines was screened to explore the mechanism of the ABAR-mediated ABA signalling. The SOAR1 gene encodes a pentatricopeptide repeat (PPR) protein which localizes to both the cytosol and nucleus. Down-regulation of SOAR1 strongly enhances, but up-regulation of SOAR1 almost completely impairs, ABA responses, revealing that SOAR1 is a critical, negative, regulator of ABA signalling. Further genetic evidence supports that SOAR1 functions downstream of ABAR and probably upstream of an ABA-responsive transcription factor ABI5. Changes in the SOAR1 expression alter expression of a subset of ABA-responsive genes including ABI5. These findings provide important information to elucidate further the functional mechanism of PPR proteins and the complicated ABA signalling network.
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影响因子：
7.2
作者：
Clough, SJ;Bent, AF
通讯作者：
Bent, AF
镁螯合酶不同成分在脱落酸信号转导中的作用
影响因子：
5.1
作者：
Du, Shu-Yuan;Zhang, Xiao-Feng;Lu, Zekuan;Xin, Qi;Wu, Zhen;Jiang, Tao;Lu, Yan;Wang, Xiao-Fang;Zhang, Da-Peng
通讯作者：
Zhang, Da-Peng
影响因子：
11.6
作者：
Abe, H;Urao, T;Yamaguchi-Shinozaki, K
通讯作者：
Yamaguchi-Shinozaki, K
影响因子：
11.6
作者：
GIRAUDAT, J;HAUGE, BM;GOODMAN, HM
通讯作者：
GOODMAN, HM
影响因子：
11.6
作者：
Gutierrez-Marcos, Jose F.;Dal Pra, Mauro;Consonni, Gabriella
通讯作者：
Consonni, Gabriella