Facial expression recognition, fear conditioning, and startle modulation in female subjects with conduct disorder.
Facial expression recognition, fear conditioning, and startle modulation in female subjects with conduct disorder.
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DOI：
10.1016/j.biopsych.2010.02.019
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发表时间：
2010-08-01
影响因子：
10.6
通讯作者：
Goodyer, Ian M.
中科院分区：
文献类型：
--
作者：
Fairchild, Graeme;Stobbe, Yvette;van Goozen, Stephanie H. M.;Calder, Andrew J.;Goodyer, Ian M.
最近的行为和心理生理学研究为品行障碍(CD)的情绪障碍提供了一致的证据。这些研究大多集中在男性受试者身上，对患有CD的女性受试者的情绪处理知之甚少。我们的主要目的是表征情绪功能的外显和内隐方面，以确定这些过程中是否存在CD女孩的缺陷。患有CD的女性青少年(n=25)和无严重反社会行为史和无精神障碍的对照组(n=30)完成了测量面部表情和面部身份识别、区分自主神经条件反射和通过图片价格对惊吓反射的情感调节的任务。与对照组相比，患有CD的参与者对愤怒和厌恶的识别能力减弱，但在面部身份识别方面没有差异。与那些心理病态特征较低的人相比，CD参与者的悲伤识别能力受损。患有CD的参与者表现出对厌恶的无条件刺激的皮肤电导反应降低，以及条件刺激之间的自主神经辨别能力受损，表明恐惧条件反射受损。患有CD的参与者在图片价格类型上也表现出惊吓程度的降低，但在情感调制模式上没有显著的组间差异。患有CD的青春期女性受试者在情绪功能的外显和内隐测试中表现出缺陷，并降低了不同输出系统的自主神经反应。然而，在情绪反应性方面没有差异。这些发现表明，患有CD的女性受试者的情绪识别和学习能力受到损害，这与先前在患有CD的男性受试者中获得的结果一致。
Recent behavioral and psychophysiological studies have provided converging evidence for emotional dysfunction in conduct disorder (CD). Most of these studies focused on male subjects and little is known about emotional processing in female subjects with CD. Our primary aim was to characterize explicit and implicit aspects of emotion function to determine whether deficits in these processes are present in girls with CD. Female adolescents with CD (n = 25) and control subjects with no history of severe antisocial behavior and no current psychiatric disorder (n = 30) completed tasks measuring facial expression and facial identity recognition, differential autonomic conditioning, and affective modulation of the startle reflex by picture valence. Compared with control subjects, participants with CD showed impaired recognition of anger and disgust but no differences in facial identity recognition. Impaired sadness recognition was observed in CD participants high in psychopathic traits relative to those lower in psychopathic traits. Participants with CD displayed reduced skin conductance responses to an aversive unconditioned stimulus and impaired autonomic discrimination between the conditioned stimuli, indicating impaired fear conditioning. Participants with CD also showed reduced startle magnitudes across picture valence types, but there were no significant group differences in the pattern of affective modulation. Adolescent female subjects with CD exhibited deficits in explicit and implicit tests of emotion function and reduced autonomic responsiveness across different output systems. There were, however, no differences in emotional reactivity. These findings suggest that emotional recognition and learning are impaired in female subjects with CD, consistent with results previously obtained in male subjects with CD.
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影响因子：
56.9
作者：
BECHARA, A;TRANEL, D;DAMASIO, AR
通讯作者：
DAMASIO, AR
影响因子：
6.9
作者：
Dolan, Mairead;Fullam, Rachael
通讯作者：
Fullam, Rachael
影响因子：
3.5
作者：
Derntl, Birgit;Kryspin-Exner, Ilse;Habel, Ute
通讯作者：
Habel, Ute
DOI：
10.1111/j.1469-7610.2008.02020.x
发表时间：
2009-05
期刊：
Journal of child psychology and psychiatry, and allied disciplines
影响因子：
--
作者：
Fairchild G;Van Goozen SH;Calder AJ;Stollery SJ;Goodyer IM
通讯作者：
Goodyer IM
影响因子：
10.5
作者：
Dadds, Mark R.;Perry, Yael;Abeygunawardane, Amali I.
通讯作者：
Abeygunawardane, Amali I.