The persistence of parasitic plasmids
The persistence of parasitic plasmids
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DOI：
10.1534/genetics.107.077420
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发表时间：
2007-09-01
期刊：
影响因子：
3.3
通讯作者：
Feil, Edward J.
中科院分区：
文献类型：
--
作者：
Lili, Loukia N.;Britton, Nicholas F.;Feil, Edward J.
预测质粒持续存在的条件仍然存在争议。在这里，我们重新评估了常微分方程模型质粒持久性和结论，维护所需的参数空间远不如假设的那么严格。引人注目的是，我们的模型表明，纯粹的寄生质粒可能会持续存在，即使在没有异质性的主机人口，这种持久性是由振荡或阻尼振荡之间的质粒轴承和质粒类。
The conditions under which plasmids are predicted to persist remain controversial. Here, we reevaluate the ordinary differential equations used previously to model plasmid persistence and conclude that the parameter space required for maintenance is far less stringent than has been supposed. Strikingly, our model demonstrates that purely parasitic plasmids may persist, even in the absence of heterogeneity in the host population, and that this persistence is expressed by oscillations or damped oscillations between the plasmid-bearing and the plasmid-free class.