The association between stress and headache: A longitudinal population-based study
The association between stress and headache: A longitudinal population-based study
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DOI：
10.1177/0333102414563087
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发表时间：
2015-09-01
期刊：
影响因子：
4.9
通讯作者：
Katsarava, Zaza
中科院分区：
文献类型：
--
作者：
Schramm, Sara H.;Moebus, Susanne;Katsarava, Zaza
我们研究了紧张型头痛(TTH)、偏头痛和偏头痛合并紧张型头痛(MigTTH)患者的压力强度和头痛频率之间的关系。方法从2010年3月至2012年4月，每季度向5159名21-71岁的受试者询问头痛和压力。结果31%的受试者(48.112.5岁，51.5%的女性，2.2+/-3.9平均头痛天数/月，52.3+/-26.7平均应激压力)，偏头痛14%(44.8+/-11.3岁，73.3%，4.5+/-5.2天/月，62.4+/-23.3岁)，偏头痛10.6%(43.5+/-11.5年，61.0%，3.6+/-4.8天/月，58.6+/-24.1岁)，23.6%无法分类，20.8%无头痛。在患有TTH的参与者中，VAS评分每增加10分，头痛天数/月增加6.0%(调整后)。较年轻年龄组的疗效较高(21-30/31-40/41-50/51-60/61-71岁：9.8/10.2/7.0/6.5/3.5%)。偏头痛(4.3%，8.1/5.1/3.4/6.3/0.3%)和MigTTH(4.2%，5.5/6.8/6.9/5.8/-0.7%)的疗效略低。
Introduction We studied the association between stress intensity and headache frequency for tension-type headache (TTH), migraine and migraine with coexisting TTH (MigTTH).Method We studied a population-based sample of 5159 participants (21-71 years) who were asked quarterly between March 2010 and April 2012 about headache and stress. Log-linear regression in the framework of generalized estimating equations was used to estimate regression coefficients presented as percent changes to describe the association between stress intensity (modified visual analog scale (VAS) from 0 to 100) and headache frequency (days/month) stratified by headache subtypes and age groups and adjusted for sex, age, frequent intake of acute pain drugs, drinking, smoking, BMI and education.Results TTH was reported in 31% participants (48.112.5years, 51.5% women, 2.2 +/- 3.9 mean headache days/month, 52.3 +/- 26.7 mean stress), migraine in 14% (44.8 +/- 11.3years, 73.3%, 4.5 +/- 5.2 days/month, 62.4 +/- 23.3), MigTTH in 10.6% (43.5 +/- 11.5 years, 61.0%, 3.6 +/- 4.8 days/month, 58.6 +/- 24.1), 23.6% were unclassifiable, and 20.8% had no headache. In participants with TTH an increase of 10 points on VAS was associated with an increase of headaches days/month of 6.0% (adjusted). Higher effects were observed in younger age groups (21-30/31-40/41-50/51-60/61-71 years: 9.8/10.2/7.0/6.5/3.5%). Slightly lower effects were observed for migraine (4.3%, 8.1/5.1/3.4/6.3/0.3%) and MigTTH (4.2%, 5.5/6.8/6.9/5.8/-0.7%).Conclusion Our study provides evidence for an association between stress intensity and headache frequency.